YN250549 Remdesivir O-desphosphate ac... 1191237-80-5

Remdesivir O-desphosphate acetonide impurity is an impurity of Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity and is highly effective in the control of SARS-CoV-2 (COVID-19) infe...

YN370454 Vonafexor 1192171-69-9

Vonafexor (EYP001) is a selectiveFXRagonist with anti-HBV effects.

YN250609 Avibactam sodium 1192491-61-4

Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor with IC50 values of 8, 80, and 38 nM for TEM-1, P99, and KPC-2 β-lactamases, respectively.

YN250608 Avibactam free acid 1192500-31-4

Avibactam free acid (NXL-104 free acid) is a covalent and reversible non-β-lactamβ-lactamaseinhibitor which inhibits β-lactamaseTEM-1 and CTX-M-15with IC50s of 8nM and 5nM, respectively.

YN250587 Cipargamin 1193314-23-6

Cipargamin (NITD609) is an potent antimalarial compound, with an IC50 of appr 1nM againstP. falciparum.

YN250607 Omadacycline hydrochloride 1196800-39-1

Omadacycline hydrochloride is novel, aminomethyl tetracycline antibiotic being developed for the treatment of community-acquired bacterial infections. The ED50 for Escherichia coliis 2.02 mg/kg.

YN250130 Vapendavir diphosphate 1198151-75-5

Vapendavir diphosphate (BTA798 diphosphate) is a potententeroviralcapsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, withEC50values of 0.5...

YN250703 Posaconazole hydrate 1198769-38-8

Posaconazole hydrate is a broad-spectrum, second generation, triazole compound withantifungalactivity.

YN250482 VCH-916 1200133-34-1

VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor.

YN250790 Targocil 1200443-21-5

Targocil functions as a bacteriostatic inhibitor of wall teichoic acid (WTA) biosynthesis which can inhibit the growth of methicillin-susceptibleS. aureus(MSSA) and methicillin-resistantS. aureus(MRSA) withMIC90s of 2 μ...

YN250957 Amphotericin B trihydrate 1202017-46-6

Amphotericin B trihydrate, a polyene antibiotic, is first isolated from fermenter cultures ofStreptomyces nodosus. Amphotericin B trihydrate also possesses antileishmanial activity.

YN250244 Chalcone 4 (hydrate) 1202866-96-3

Chalcone 4 hydrate is ananti-parasiteagent, inhibits the growth ofBabesia and Theileria.

YN372282 Grazoprevir potassium salt 1206524-86-8

Grazoprevir potassium salt (MK-5172 potassium salt) is a selective inhibitor ofHepatitis C virus NS3/4aprotease with broad activity across genotypes and resistant variants, with Kis of 0.01nM (gt1b), 0.01nM (gt1a), 0.08nM (gt2a...

YN371040 Paritaprevir 1216941-48-8

Paritaprevir (ABT-450) is a nonstructural (NS) protein 3/4A protease inhibitor.

YN250014 Delpazolid 1219707-39-7

Delpazolid is a novel oxazolidinone antibiotic agent which can inhibit the growth of MSSA and MRSA with a MIC90 of 2 μg/mL for both of them.

YN250350 G0507 1223998-29-5

G0507, a pyrrolopyrimidinedione compound, is a potentLolCDE ABC Transporterinhibitor. G0507 is a inhibitor ofEscherichia coligrowth and induces the extracytoplasmic σE stress response. G0507 acts as a chemical probe to disse...

YN250821 Brilacidin tetrahydrochloride 1224095-99-1

Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is an anti-infective antimicrobial with MIC90s of 1 and 8 μg/mL for Gram-positive bacteriaStreptococcus pneumonia and Streptococcus viridans, and MIC90 of 8 an...

YN250776 Cefiderocol 1225208-94-5

Cefiderocol (S-649266) is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negativebacterialspecies withMIC50s of 2 μg/mL or less.

YN250355 Epetraborole hydrochloride 1234563-16-6

Epetraborole hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor, which inhibits protein synthesis by binding "to the terminal adenosine ribose (A76) of leucyl-tRNA synthetase". It is intended for the treatment of ...

YN484020 Competence-Stimulating Pept... 1235882-91-3

Competence-Stimulating Peptide-12261, a sixteen peptide, is a fragment of competence-stimulating peptide. Competence-Stimulating Peptide, a quorum-sensing molecule, competence-stimulating peptide (CSP) which inhibits germ tube (GT...