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Infection

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN320533 ASP6432 1282549-08-9

    ASP6432 is a potent and selectivetype 1 lysophosphatidic acid receptor (LPA1)antagonist with IC50s of 11nM and 30nM for human LPA1 and rat LPA1, respectively.

  • YN484158 Influenza Matrix Protein (6... 1286245-45-1

    Influenza Matrix Protein (61-72) is a peptide fragment derived from matrix protein of influenza viruses, corresponds to amino acids 61-72. Influenza Matrix Protein (61-72) is a specific epitope which can induce CD4+T-cell response.

  • YN251178 Sulfamonomethoxine D4 1286538-12-2

    Sulfamonomethoxine D4 is a deuterium labeled Sulfamonomethoxine. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies, and blocks the synthesis of folic acid by inhibiting synthetase of dih...

  • YN420263 Miransertib 1313881-70-7

    Miransertib (ARQ-092) is a potent, selective and orally bioavailable allosteric inhibitor of Akt with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively.

  • YN320778 CYM50358 1314212-39-9

    CYM50358 is a potent and selectiveS1PR4antagonist, with an IC50 of 25nM. CYM50358 can be used for the research of influenza infection.

  • YN250799 Azvudine hydrochloride 1333126-31-0

    Azvudine (RO-0622) hydrochloride is a potentnucleoside reverse transcriptaseinhibitor (NRTI), with antiviral activity onHIV,HBV and HCV. Azvudine hydrochloride exerts highly potent inhibition on HIV-1 (EC50s ranging fr...

  • YN250688 Eravacycline dihydrochloride 1334714-66-7

    Eravacycline dihydrochloride (TP-434 dihydrochloride) is a potent and broad-spectrumantibacterialagent.

  • YN250048 Q203 1334719-95-7

    Q203 (IAP6) is a midazopyridine amide compound. Q203 is active against Mycobacterium tuberculosisH37Rv with an MIC50 of 2.7nM in culture broth medium.

  • YN250682 Doravirine 1338225-97-0

    Doravirine is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT) and K103N and Y181C reverse transcriptase (RT) mutants, respectively, in a biochem...

  • YN250075 AU1235 1338780-86-1

    AU1235, an adamantyl urea, is a potent inhibitor of Mycobacterium tuberculosis protein MmpL3.

  • YN372466 Oteseconazole 1340593-59-0

    Oteseconazole (VT-1161) is an orally activeanti-fungalagent, potently binds to  and  inhibitsC and ida albicansCYP51(Kd, <39nM), shows no obvious effect on human CYP51.

  • YN372281 Grazoprevir 1350514-68-9

    Grazoprevir anhydrous is a Hepatitis C Virus NS3/4A Protease inhibitor with IC50 values of 7pM, 4pM, and 62pM for HCV genotype 1a, 1B, and 4 respectively.

  • YN250685 Lefamulin acetate 1350636-82-6

    Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase c...

  • YN250295 PF-3450074 1352879-65-2

    PF-3450074 (PF-74) is a specifical inhibitor ofHIV-1 capsid protein (CA) and displays a broad-spectrum inhibition of HIV isolates with submicromolar potency (EC50=8-640nM). PF-3450074 (PF-74) acts at an early stage of H...

  • YN250676 Presatovir 1353625-73-6

    Presatovir (GS-5806) is an orally bioavailableRSVfusion inhibitor with a mean EC50 value of 0.43nM.

  • YN250960 Albendazole D3 1353867-92-1

    Albendazole D3 is the deuterium labeled Albendazole, which is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.

  • YN250772 Rafoxanide 13C6 1353867-98-7

    Rafoxanide 13C6 is a labeled Rafoxanide (HY-17598). Rafoxanide is a salicylanilide used as an antiparasitic agent.

  • YN250067 Pibrentasvir 1353900-92-1

    Pibrentasvir (ABT-530) is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50 ranging from 1.4 pM to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6.

  • YN250570 ELQ-300 1354745-52-0

    ELQ-300 is a potent and orally bioavailableantimalarialagent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1complex (cyt bc1).

  • YN371052 GS-443902 trisodium 1355050-21-3

    GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viralRNA-dependent RNA-polymerases (RdRp)inhibitor with IC50s of 1.1 µM, 5 µM forRSVRdRp and HCVRdRp, respectively. GS-443902 trisodium is the...

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