Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN371051 GS-443902 1355149-45-9
GS-443902 (GS-441524 triphosphate) is a potent viralRNA-dependent RNA-polymerases (RdRp)inhibitor with IC50s of 1.1 µM, 5 µM forRSVRdRp and HCVRdRp, respectively. GS-443902 is the active triphosphate metabolit...
OG-L002 is a potent and specific LSD1 inhibitor with IC50 of 20 nM in a cell-free assay, exhibiting 36- and 69-fold selectivity over MAO-B and MAO-A, respectively.
YN250232 BRD-K98645985 1357647-78-9
BRD-K98645985 is aBAF (mammalian SWI/SNF) transcriptional repressioninhibitor with an EC50 of ~2.37 µM. BRD-K98645985 binds ARID1A-specificBAFcomplexes, prevents nucleosomal positioning, and potently reversesH...
YN251614 Isoforsythiaside 1357910-26-9
Isoforsythiaside, isolated fromForsythia suspensa, is an antioxidant and antibacterial phenylethanoid glycoside with MICs of 40.83, 40.83, and 81.66 μg/mL forEscherichia coli(E. coli),Pseudomonas aeruginosa(PAO), and Stap...
YN250198 (3R,4R)-A2-32-01 1359752-95-6
(3R,4R)-A2-32-01 (compound 2), an anti-virulence drug, is a specificcaseinolytic protein proteases (ClpP)inhibitor with an EC50 of 4.5μM, and shows a tolerable cytotoxicity.
YN250825 Vaborbactam 1360457-46-0
Vaborbactam (RPX7009) is a cyclic boronic acid pharmacophoreβ-lactamaseinhibitor.
YN372463 Glecaprevir 1365970-03-1
Glecaprevir is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor that targets the the viral RNA replication. It displays IC50 values ranging from 3.5 to 11.3 nM for clinical isolates of HCV geno...
YN360295 Lotilaner 1369852-71-0
Lotilaner is aparasiticide, acts as a potent non-competitive antagonist of insectsGABACl receptors, with an IC50 of 23.84nM forDrosophila melanogasterGABA receptor. No effect on a dog GABAA receptor.
RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses.
YN250656 Elbasvir 1370468-36-2
Elbasvir is an NS5A inhibitor, preventing hepatitis C viral RNA replication and virion assembly. Median EC50 values range from 0.2 to 3600 pmol/L, based on genotype.
M4284 is a selective and orally active biphenyl mannosideFimHantagonist. M4284 has activities against different UPEC (Urinary tract infections (UTI) caused by uropathogenicE. coli) strains in different host genetic background...
YN250422 Macozinone 1377239-83-2
Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potentDprE1(decaprenylphosphoryl-β-d-ribose 2′-oxidase) inhibitor. Macozinone inhibits the essential flavoprotein DprE1 by forming a covalent bond with the active-s...
Ribocil is a highly selective chemical modulator of bacterial riboflavin riboswitches. Ribocil strongly inhibits GFP expression, achieving a 50% effective concentration (EC50) of 0.3μM. in vitro: Ribocil is a highly specific bioac...
JNJ-678 (JNJ-53718678) is a novelfusion proteininhibitor. JNJ-678 has the potential forrespiratory syncytial virus (RSV) treatment.
SPR719 (VXc-486) is agyrase Binhibitor, with bactericidal activity. SPR719 potently inhibits multiple drug-sensitive isolates and drug-resistant isolates ofMycobacterium tuberculosis, with MICs of 0.03 to 0.30 μg/ml and 0....
YN250488 Lamivudine 13C,15N2 1391052-30-4
Lamivudine 13C,15N2 is a labelled impurity of Lamivudine (BCH-189). Lamivudine is a nucleoside reverse transcriptase inhibitors (NRTIs), and can inhibit HIV reverse transcriptase 1/2 and the reverse transcriptase of hepat...
YN250489 Sulfadimethoxypyrimidine D4 1392211-88-9
Sulfadimethoxypyrimidine D4 is a deuterium labeled Sulfadimethoxypyrimidine. Sulfadimethoxypyrimidine is a sulfonamide antibiotic with a broad-spectrum antibacterial effect.
YN250623 Tenofovir alafenamide hemifum... 1392275-56-7
Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse tra...
YN250677 Sarolaner 1398609-39-6
Sarolaner (PF-6450567) is an orally active, broad-spectrum ectoparasiticide, has efficacy against fleas and ticks on dogs, with LC80of 0.3 μg/mL againstC. felis and an LC100of 0.003 μg/mL againstO. turicata.
YN320622 (R)-Praziquantel D11 1399880-38-6
(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer.
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