Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN481548 Linerixibat 1345982-69-5
Linerixibat (GSK2330672) is a highly potent, nonabsorbable and orally activeapical sodium-dependent bile acid transporter (ASBT)inhibitor with an IC50 of 42nMhuman ASBT. Linerixibat can be used as lipid-loweri...
GSK'872 (GSK2399872A) is a potent and selective RIP3 kinase inhibitor which binds RIP3 kinase domain with high affinity (IC50=1.8 nM) and inhibits kinase activity with IC50 of 1.3 nM. It has minimal cross-reactivity.
YN330352 Avacopan 1346623-17-3
Avacopan (CCX168) is an orally administered and selective C5a receptor (C5aR) antagonist.
YN320689 Phenylethanolamine A 1346746-81-3
Phenylethanolamine A acts as aβ-adrenergicagonist. Phenylethanolamine A is a byproduct during the Ractopamine synthesis process.
YN260074 Propargyl-PEG3-acid 1347760-82-0
Propargyl-PEG3-acid is a non-cleavable (3 unit PEG) ADC linker and also a PEG-based PROTAC linker that can be used to synthesis 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA (HY-B1081, HY-B108...
YN480961 Antitumor agent-2 1351163-57-9
Antitumor agent-2 is sourced from patent CN102250203, compound 6a-r, has antitumor action and anti-inflammatory action.
CMS-121 is a quinolone derivative and an orally activeacetyl-CoA carboxylase 1 (ACC1)inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage withEC50values of 7nM and 200nM, respectively. CMS-1...
YN320690 Brombuterol D9 hydrochloride 1353867-94-3
Brombuterol D9 hydrochloride (Bromobuterol D9 hydrochloride) is a deuterium labeled Brombuterol hydrochloride. Brombuterol hydrochloride is aβ-adrenergic receptoragonist.
YN320691 Brombuterol D9 1353940-55-2
Brombuterol D9 (Bromobuterol D9) is a deuterium labeled Brombuterol. Brombuterol is aβ-adrenergic receptoragonist.
YN420252 Leniolisib 1354690-24-6
Leniolisib(CDZ 173) is a potent PI3Kδ selective inhibitor with biochemical IC50 values of 0.244, 0.424, 2.23 and 0.011 μM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.
YN480873 DMT1 blocker 1 1354790-56-9
DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64μM, is expected to block iron uptake by enterocytes in vivo.
C25-140, a first-in-class, orally active, and fairly selectiveTRAF6-Ubc13inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reducesNF-κBactivation, ...
BRD5529 is a selectiveCARD9-E3 ubiquitin ligase TRIM62protein-protein interaction inhibitor with an IC50 of 8.6μM. BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-m...
SR2211 is a potent, selective syntheticRORγmodulator and functions as an inverse agonist, with a Ki of 105nM and an IC50 of ~320nM.
YN483344 Caulophylline B 1359978-55-4
Caulophylline B is a fluorenone alkaloid isolated from the roots ofCaulophyllum robustumMaxim, affords a low scavenging effect against DPPH radical.
LDC1267 is a highly selective TAM kinase inhibitor with IC50 of <5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8.
YN420245 Seletalisib 1362850-20-1
Seletalisib is a novel small-molecule inhibitor of PI3Kδ with an IC50 value of 12 nM and shows significant selectivity to PI3Kδ with respect to the other class I PI3K isoforms (between 24- and 303-fold).
YN260071 Biotin-PEG2-acid 1365655-89-5
Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
AX-024 is an orally available, first-in-class inhibitor of theTCR-Nckinteraction that selectively inhibits TCR-triggered T cell activation with anIC50~1nM. AX-024 modulates cell signaling by targetingSH3domains. AX-024 ha...
YN372311 LY 3000328 1373215-15-6
LY 3000328 is a potent and selectiveCathepsin S (Cat S)inhibitor with IC50s of 7.7 and 1.67nM for hCat S and mCat S, respectively.
TELL : +86-020-82000279
Add:Room 519, Block F, Guangzhou International Business Incubator, No.3 Lanyue Road, Science Town, Huangpu District, Guangzhou, China.
