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Metabolic Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN470015 3-O-(2-Aminoethyl)-25-hydrox... 163018-26-6

    3-O-(2-Aminoethyl)-25-hydroxyvitamin D3 is a Vitamin D3 derivative.

  • YN482904 Kukoamine B 164991-67-7

    Kukoamine B is a component of Lycii Cortex, with anti-oxidant, anti-acute inflammatory and anti-diabetic properties.

  • YN330259 Urolithin C 165393-06-6

    Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator ofinsulin secretion. Urolithin C is aL-type Ca2+channelopener and enhancesCa2+influx. Urolithin C induces cellapoptosisthrough a mitochond...

  • YN360479 BMS-191095 166095-21-2

    BMS-191095 is an activators of mitochondrial ATP-sensitive potassium (mitoKATP) channels.

  • YN270548 Eriosematin 168010-17-1

    Eriosematin is a compound from the roots ofFlemingia philippinensiswith antiproliferative activity and apoptosis-inducing property.

  • YN322071 CCK-B Receptor Antagonis... 168161-71-5

    CCK-B Receptor Antagonist 1 is an antagonist of cholecystokinin B(CCK-B) receptor, and has the potential of reducing the secretion of gastric acid.

  • YN320821 Rimonabant 168273-06-1

    Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane.

  • YN321815 SHU 9119 168482-23-3

    SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partialMC5Ragonist; with IC50 values of 0.23, 0.06, and 0.09nM for human MC3R, MC4R and MC5R, respectively.

  • YN370344 SY-640 168705-70-2

    SY-640 is an Acetamide derivative and has potent hepatoprotective effect. SY-640 reduces Propionibacterium acnes and Lipopolysaccharide-induced liver injury in mice.

  • YN370761 1,2-Dipalmitoyl-sn-glycerol 3... 169051-60-9

    1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite

  • YN320133 RS 17053 hydrochloride 169505-93-5

    RS 17053 hydrochloride is a potent and selectiveα1Aadrenoceptorantagonist, with apKivalue of 9.1 in native cell membrane and apA2value of 9.8 in functional assays.

  • YN310052 Ruboxistaurin hydrochloride 169939-93-9

    LY333531 is a β-specific protein kinase C inhibitor. It competitively and reversibly inhibits PKCβ1 and PKCβ2 with IC50 values of 4.7 and 5.9 nM respectively.

  • YN270613 Infliximab 170277-31-3

    Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds toTNF-α. Infliximab prevents the interaction ofTNF-αwith TNF-α receptor (TNFR1 and TNFR2). Infliximab has the potential for auto...

  • YN370367 CD2665 170355-78-9

    CD2665 is a selectiveRAR-beta/gammaantagonist, with Ki values of 110nM, 306nM for RARγ and RARβ, respectively.

  • YN320031 KW-8232 free base 170365-25-0

    KW-8232 free base is an anti-osteoporotic agent, and can reduces the biosynthesis of PGE2.

  • YN481244 Glycosidase-IN-1 170376-12-2

    Glycosidase-IN-1 (Compound 9) is aglycosidaseinhibitor synthesized from D-mannose. Glycosidase-IN-1 be used to synthesize some immunosuppressive agents and β-glucosidase inhibitors. Glycosidase-IN-1 has hypoglycemic activity.

  • YN340136 AG-1478 hydrochloride 170449-18-0

    AG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selectiveEGFRtyrosine kinase inhibitor with IC50 of 3nM. AG-1478 hydrochloride has antiviral effects againstHCV and encephalomyocarditis virus (EMCV).

  • YN483764 Cholecystokinin Octapeptide,... 171486-94-5

    Cholecystokinin Octapeptide, desulfated TFA is a synthetic desulfated octapeptides of Cholecystokinin (CCK).

  • YN483151 Sibirioside A 173046-19-0

    Sibirioside A is a phenylpropanoid glycoside isolated fromScrophulariae Radix. Sibirioside A has the potential for the treatment of diabetes.

  • YN470007 TEI-9647 173388-20-0

    TEI-9647 is a first and potentVDR/vitamin D-responsive element (DRE)-mediated genomic actions antagonist. TEI-9647 is a 1α,25-dihydroxyvitamin D3-26,23-lactone (1α,25-lactone) analogue.

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