YN480742 Homobaldrinal 67910-07-0

Homobaldrinal is adecomposition productof Valepotriate (HY-N0718). Homobaldrinal exhibits genotoxic activity in the Salmonella/microsome test.

YN321941 Substance P(1-7) 68060-49-1

Substance P(1-7) is a fragment of the neuropeptide, substance P (SP). Substance P(1-7) gives depressor and bradycardic effects when applied to the nucleus tractus solitarius.

YN360176 (2S)-6-Prenylnaringenin 68236-13-5

(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as aGABAApositive allosteric modulator at α+β- binding interface.

YN481604 (R)-Oxiracetam 68252-28-8

(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam (ISF 2522) is a nootropic drug of the racetam family and stimulant.

YN360739 Zonisamide 68291-97-4

Zonisamide is a voltage-dependent sodium channel and T-type calcium channel blocker, used as an antiepileptic drug.

YN360740 Zonisamide sodium 68291-98-5

Zonisamide sodium (AD 810 sodium; CI 912 sodium) is an inhibitor of zinc enzymecarbonic anhydrase (CA), with Kis of 35.2nM and 20.6nM for human mitochondrial isozyme hCA II and hCA V, respectively. Zonisamide sodium ha...

YN484265 Verilopam 68318-20-7

Verilopam is a potent analgesic.

YN481586 Pramiracetam 68497-62-1

Pramiracetam is a more potent nootropic drug derived from piracetam.

YN360534 Vigabatrin 68506-86-5

Vigabatrin (γ-Vinyl-GABA), a inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminaseinhibitor. Vigabatrin is an antiepileptic agent, which acts by increasing GABA level...

YN360055 Isoguvacine hydrochloride 68547-97-7

Isoguvacine hydrochloride is a GABA receptor agonist.

YN350223 (Rac)-Hesperetin 69097-99-0

(Rac)-Hesperetin is the racemate of Hesperetin. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against humanUGTactivity. Hesperetin induces apoptosis via p38 MAPK activation.

YN270574 Gomisin N 69176-52-9

Gomisin N, isolated from Schis and ra chinensis, produces beneficial sedative and hypnotic bioactivity. Gomisin N has the potential for use in the treatment of allergy. Gomisin N is an anti-cancer drug c and idate capable of inhibi...

YN360610 (R)-Baclofen 69308-37-8

(R)-baclofen is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.

YN483940 ACTH (34-39) 69454-10-0

ACTH (34-39) is an adrenocorticotropic hormone fragment.

YN360202 Pivagabine 69542-93-4

Pivagabine (CXB 722) is a hydrophobic 4-aminobutyric acid derivative with neuromodulatory activity. Pivagabine penetrates the blood-brain barrier in rats. Pivagabine antagonizes the effects of foot shock on both GABAA receptor f...

YN361092 GI-530159 69563-88-8

GI-530159 is a selective, mechanosensitive opener ofTREK1 (K2P2.1) and TREK2 (K2P10.1) channels, with an EC50 of 0.76μM for TREK1. GI-530159 displays selectivity for TREK1/2 over TRAAK, TASK3 and other...

YN480257 18:0 LYSO-PE 69747-55-3

18:0 LYSO-PE is an agent that can induce [Ca2+]iincrease.

YN330189 Pelubiprofen 69956-77-0

Pelubiprofen, an orally active and non-steroidal anti-inflammatory drug, is a member of the 2-arylpropionic acid family and has relatively selective effects onCOX-2activity. Pelubiprofen inhibits COX activity and the transform...

YN1730067 ABT-724 70006-24-5

ABT-724 is a potent and highly selectivedopamine D4receptoragonist with an EC50 of 12.4nM forhuman dopamine D4receptor. ABT-724 is a potent partial agonist at therat D4(EC50of 14.3nM) and theferret D4receptor(EC50of 23...

YN380265 Obtusin 70588-05-5

Obtusin, isolated fromCassia obtusifoliaLinn seed, is a highly selective and competitivehuman monoamine oxidase-A (hMAO-A)inhibitor with an IC50 of 11.12μM and a Ki of 6.15μM. Obtusin plays a preventive role in neurodege...