YN322062 Vinconate 70704-03-9

Vinconate is an indolonaphthyridine derivative and can stimulate themuscariic acetylcholine receptor.

YN360456 5-Hydroxydecanoate sodium 71186-53-3

5-Hydroxydecanoate sodium is a selectiveATP-sensitive K+(KATP)channel blocker (IC50 of ~30μM). 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase and has antioxidant activity.

YN380179 Moclobemide 71320-77-9

Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM.

YN1730072 Amisulpride 71675-85-9

Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.

YN370061 Sp-cAMPS 71774-13-5

Sp-cAMPS, a cAMP analog, is potent activator of cAMP-dependent PKA I and PKA II. Sp-cAMPS is also a potent, competitivephosphodiesterase (PDE3A) inhibitor with a Ki of 47.6 µM. Sp-cAMPS binds the PDE...

YN483897 Substance P, Free Acid 71977-09-8

Substance P, Free Acid is a native substance P analog, but shows no biological activity of substance P.

YN482513 Spinosin 72063-39-9

Spinosin ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. Spinosin...

YN321795 β-Casomorphin, bovine 72122-62-4

β-Casomorphin, bovine (β-Casomorphin-7 (bovine) ) is aopioidpeptide with an IC50 of 14μM in an Opioid receptors binding assay.

YN371545 Apovincaminic acid hydrochlor... 72296-47-0

Apovincaminic acid hydrochloride salt is an orally active and brain-penetrant main active metabolite of Vinpocetine (VP). Apovincaminic acid hydrochloride salt exerts a neuroprotective type of action.

YN360234 Aniracetam 72432-10-1

Aniracetam is a nootropics and neuroprotective drug.

YN481576 Miglustat 72599-27-0

Miglustat (Zavesca, N‐butyldeoxynojirimycin, OGT 918) is an orally administered ceramide glucosyltransferase inhibitor which prevents the lysosomal accumulation of glucocerebroside.

YN320811 ICI 118,551 hydrochloride 72795-01-8

ICI 118,551 (hydrochloride) is a highly selectiveβ2 adrenergic receptorantagonist, with Kis of 0.7, 49.5 and 611nM for β2, β1 and β3 receptors, respectively.

YN321315 Tianeptine 72797-41-2

Tianeptine is an antidepressant agent that act as an atypical agonist of the μ-opioid receptor with clinically negligible effects on the δ- and κ-opioid receptors.

YN361060 Darodipine 72803-02-2

Darodipine (PY 108-068, PY-108068) is a potentcalcium channelantagonist.

YN361088 CyPPA 73029-73-9

CyPPA is a positive modulator ofhSK3 and hSK2, withEC50values of 14μM and 5.6μM, repectively. CyPPA is inactive on both hSK1 and hIK channels.

YN481181 1-(Anilinocarbonyl)proline 73096-22-7

1-(Anilinocarbonyl)proline can be used to identify dual action probes in a cell model of Huntington.

YN483264 Effusol 73166-28-6

Effusol, a phenolic constituent fromJuncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC50 values of 79μM and 2.73μM, respectively. Effusol rescues CA1 LTP attenuated by corticost...

YN440019 Rp-cAMPS 73208-40-9

Rp-cAMPS, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependentPKA I and II(Kis of 12.5 µM and 4.5 µM, respectively) antagonist. Rp-cAMPS is resistant to hydrolysis by phosphodie...

YN480889 Apraclonidine hydrochloride 73218-79-8

Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.

YN250710 Mevastatin 73573-88-3

Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself.