YN360007 Pipequaline 77472-98-1

Pipequaline (PK 8165) is a partialbenzodiazepine receptoragonist with anxiolytic activity.

YN322094 Opioid receptor modulator 1 77514-44-4

Opioid receptor modulator 1 is aopioid receptormodulator extracted from patent WO2014072809A2, Compound RA11 in EXAMPLE 7.

YN360058 (RS)-AMPA 77521-29-0

(RS)-AMPA ((±)-AMPA) is a glutamate analogue and a potent and selective excitatory neurotransmitterL-glutamic acidagonist. (RS)-AMPA does not interfere with binding sites for kainic acid or nMDA receptors.

YN370090 GNF-PF-3777 77603-42-0

GNF-PF-3777 (8-Nitrotryptanthrin) is a potent humanindoleamine 2,3-dioxygenase2 (hIDO2) inhibitor which significantly reduces IDO2 activity with Kiof 0.97μM.

YN321821 Dermorphin 77614-16-5

Dermorphin is a natural heptapeptideμ-opioid receptor(MOR) agonist found in amphibian skin. Inhibition of neuropathic pain.

YN482805 6‴-Feruloylspinosin 77690-92-7

6‴-Feruloylspinosin is a flavonoid isolated from seeds ofZiziphus jujuba. 6‴-Feruloylspinosin can across the blood-brain barrier and enhance the expression of GABAAα1, GABAAα5, and GABABR1 mRNA in rat hippocamp...

YN380177 Paroxetine hydrochloride 78246-49-8

Paroxetine HCl is an antidepressant drug of the SSRI type.

YN321216 2-Methyl-5-HT 78263-90-8

2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective5-HT3receptoragonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects.

YN321218 2-Methyl-5-HT maleate 78263-91-9

2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective5-HT3receptoragonist. 2-Methyl-5-HT maleate is shown to display anti-depressive-like effects.

YN321822 Dermorphin TFA 78331-26-7

Dermorphin TFA is a natural heptapeptideμ-opioid receptor(MOR) agonist found in amphibian skin. Inhibition of neuropathic pain.

YN360063 FG 7142 78538-74-6

FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor(Ki=91nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride...

YN270499 Astramembrangenin 78574-94-4

Astramembrangenin (Cycloastragenol) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient inAstragalus membranaceus(Fisch.) Bunge. Astramembrangenin is orally safe and has broad Extensive pharm...

YN360727 Flumazenil 78755-81-4

Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.

YN360017 Sarmazenil 78771-13-8

Sarmazenil is abenzodiazepine receptorantagonist.

YN322033 Cyclodrine hydrochloride 78853-39-1

Cyclodrine hydrochloride is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.

YN320446 8-OH-DPAT 78950-78-4

8-OH-DPAT is a potent and selective5-HTagonist, with apIC50 of 8.19 for 5-HT1A and a Ki of 466nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50<5).

YN360044 D-AP5 79055-68-8

D-AP5 (D-APV) is a selective and competitive NMDA receptorantagonist with aKdof 1.4μM. D-AP5 (D-APV) inhibits the glutamate binding site of NMDA receptors.

YN482579 Deoxyandrographolide 79233-15-1

Deoxy and rographolide, isolated from the and rographis paniculata, suppresses LPS induced increase in mRNA levels of iNOS as well as production of proinflammatory mediators TNF-α and IL-6. Deoxy and rographolide potentia...

YN483898 Somatostatin-28 1-14 79243-10-0

Somatostatin-28 (1-14) is an N-terminal fragment of the neuropeptide somatostatin-28.

YN484180 Mioflazine 79467-23-5

Mioflazine is an orally activenucleoside transportinhibitor, has the potential for sleep disorders treatment. Mioflazine inhibits nucleoside uptake.