YN320877 Olanzapine 132539-06-1

Olanzapine is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.

YN321913 [Leu31,Pro34]-Neuropeptide ... 132699-73-1

[Leu31,Pro34]-Neuropeptide Y(human,rat) is a specificneuropeptide Y Y1receptoragonist. [Leu31,Pro34]-Neuropeptide Y(human,rat) slao inhibits Y4, Y5. [Leu31,Pro34]-Neuropeptide Y(human,rat) can increase blood pressure in ane...

YN320759 Blonanserin 132810-10-7

Blonanserin (AD-5423) is a potent  and orally active5-HT2A(Ki=0.812nM) and dopamine D2 receptor(Ki=0.142 nM) antagonist. Blonanserin is usually acts as an atypical antipsychotic agent and can be used for the research of...

YN320514 Org-12962 132834-56-1

Org-12962 is a potent, selective and orally active5-HT2Creceptoragonist with apEC50value of 7.01. Org-12962 also exhibits high effacy for the 5-HT2A and 5-HT2Breceptor withpEC50s of 6.38 and 6.28, respectively.Org-12962...

YN321544 Ramosetron Hydrochloride 132907-72-3

Ramosetron Hydrochloride is the hydrochloride salt of ramosetron, a selective serotonin (5-HT) receptor antagonist with potential antiemetic activity.

YN321264 (±)-Darifenacin 133033-93-9

(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective M3 muscarinic receptor antagonist.

YN1730121 KFM19 133058-72-7

KFM19 is a potent, selectiveAdenosine receptor(A1-receptor) antagonist, with an IC50 of 50nM.

YN360076 ZD7288 133059-99-1

ZD7288 (ICI D7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.

YN321336 Darifenacin 133099-04-4

Darifenacin(UK88525) is a selective M3 muscarinic receptor antagonist with pKi of 8.9.

YN321322 Darifenacin hydrobromide 133099-07-7

Darifenacin is a selective M3 muscarinic receptor antagonist with pKi of 8.9.

YN321206 EMD 56551 133109-86-1

EMD 56551 is a potent and selective5-HT1A receptoragonist. EMD 56551 exerts anxiolytic activity.

YN321861 GR-73632 133156-06-6

GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals.

YN372402 Lactacystin 133343-34-7

Lactacystin, an antibioticStreptomycesspp. metabolite, is a potent and selectiveproteasomeinhibitor with an IC50 of 4.8μM for 20S proteasome. Lactacystin also inhibits the lysosomal enzyme cathepsin A. Lactacystin inhibits cell ...

YN320124 ST034307 133406-29-8

ST034307 is a potent and selectiveadenylyl cyclase 1 (AC1)inhibitor, with IC50 of 2.3μM.

YN321132 Iloperidone 133454-47-4

Iloperidone is a dopamine (D2)/serotonin (5-HT2) receptor antagonist, used for the treatment of schizophrenia.

YN360089 Ralfinamide 133865-88-0

Ralfinamide (FCE-26742A) is an orally available Na+blocker derived from α-aminoamide, with function of suppressing pain.

YN380147 Safinamide 133865-89-1

Safinamide is an orally active, selective, reversible monoamine oxidase-B inhibitor with both dopaminergic and non-dopaminergic (glutamatergic) properties. The IC50 value of safinamide for MAO-B is 98 nM.

YN360104 TDN345 134069-68-4

TDN345 is aCa2+antagonist, used for the treatment of vascular and senile dementia including Alzheimer's disease.

YN361097 Traxoprodil 134234-12-1

Traxoprodil (CP101,606) is a potent and selectiveNMDAantagonist and protect hippocampal neurons with an IC50 of 10nM.

YN372433 Tolcapone 134308-13-7

Tolcapone is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM.