YN320885 Talnetant 174636-32-9

Talnetant (SB 223412) is a potent and selective NK3 receptor antagonist (ki=1.4nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM. in vit...

YN321869 CH 275 174688-78-9

CH 275 is a potent and selectivesomatostatin receptor 1 (sst1)agonist and displayIC50 values of 30.9nM, 345nM, >1 μM, >10 μM for human human sst1, sst3, sst4, sst2 and sst5respectively. CH 275 can be used for the research...

YN482788 Parishin C 174972-80-6

Parishin C, a parishin derivative isolated fromGastrodia elata, may have antioxidant property.

YN300039 Tonabersat 175013-84-0

Tonabersat (SB-220453) is agap-junctionmodulator. Tonabersat prevents inflammatory damage in the central nervous system .

YN380166 Milnacipran ((1S-cis) hydroc... 175131-60-9

Levomilnacipran Hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor with antidepressant activity.

YN320819 CP 316311 175139-41-0

CP 316311 is a potent and selectiveCRF1 receptorantagonist with an IC50 value of 6.8nM.

YN320820 CP 376395 175140-00-8

CP 376395 is a potent and selectiveCorticotropin releasing factor 1 (CRF1)receptor antagonist.

YN360238 S 18986 175340-20-2

S 18986 is a selective, orally active, brain penetrant positive allosteric modulator ofAMPA-typereceptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in...

YN360454 5-AAM-2-CP 175424-74-5

5-AAM-2-CP is a major metabolite of Acetamiprid. Acetamiprid is a neonicotinoid insecticide used worldwide and is anAChRagonist.

YN361052 α-Conotoxin MII 175735-93-0

α-Conotoxin MII (α-CTxMII), a 16-amino acid peptide from the venom of the marine snail Conus magus, potently blocksnicotinic acetylcholine receptors (nAChRs)composed ofα3β2subunits, with an IC50 of 0.5nM. α-Conotoxin M...

YN321199 Eglumegad 176199-48-7

Eglumegad (LY354740) is a highly potent and selectivegroup II (mGlu2/3) receptoragonist with IC50s of 5 and 24nM on transfected human mGlu2 and mGlu3 receptors, respectively.

YN321893 Urocortin, human 176591-49-4

Urocortin, human, a 40-aa neuropeptide, acts as a selective agonist of endogenousCRF2receptor, with Kis of 0.4, 0.3, and 0.5nM for hCRF1, rCRF2α and mCRF2β, respectively.

YN322102 LY320135 176977-56-3

LY320135 is a potent and selective antagonist ofCB1receptor, with a Ki of 141nM. LY320135 also binds to5-HT2 and muscarinic receptorswith Kis of 6.4μM and 2.1μM, respectively. LY320135 exhibits neuroprotective effect.

YN321172 NKP608 177707-12-9

NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6nM) and in vivo. In vitro, the binding of NKP608 t...

YN321321 Eletriptan hydrobromide 177834-92-3

Eletriptan is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively.

YN321907 Nociceptin (1-13), amide 178064-02-3

Nociceptin (1-13), amide is a potentORL1 (OP4) receptoragonist with apEC50of 7.9 for mouse vas deferens and a Ki of 0.75nM for binding to rat forebrain membranes.

YN321899 Orphanin FQ(1-11) 178249-41-7

Orphanin FQ(1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potentNOP receptor (ORL-1; OP4)agonist, with a Ki of 55nM. Orphanin FQ(1-11) has no affinity for μ, δ, κ1 and κ3 receptors (Ki>1000nM). Orp...

YN322083 Tachykinin angatonist 1 178310-77-5

Tachykinin angatonist 1 is aneurokinin receptorantagonist extracted from patent US5968923, compound example 32.

YN1730030 Solriamfetol 178429-62-4

Solriamfetol (JZP-110) is an orally active and selectivedopamine and norepinephrine reuptakeinhibitor with IC50s of 2.9μM and 4.4μM for dopamine and norepinephrine transporters, respectively. Solriamfetol has robust wake-...

YN1730031 Solriamfetol hydrochloride 178429-65-7

Solriamfetol hydrochloride (JZP-110 hydrochloride) is an orally active and selectivedopamine and norepinephrine reuptakeinhibitor with IC50s of 2.9μM and 4.4μM for dopamine and norepinephrine transporters, respectively. S...