YN320884 Osanetant 160492-56-8

Osanetant (SR142801) is a selectiveNK3 receptorantagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for schizophrenia.

YN360220 DMP-543 160588-45-4

DMP-543 (XR-543) is aKV7 channelblocker, also acts as a potent neurotransmitter release enhancer.

YN380016 SPD-473 citrate 161190-26-7

SPD-473 citrate is aserotonin/dopamine/norepinephrinereuptake inhibitior.

YN482759 Cimigenol-3-O-α-L-arabinos... 161207-05-2

Cimigenol-3-O-α-L-arabinoside is a triterpenoid isolated fromCimicifuga foetidaL.

YN360522 MDL 105519 161230-88-2

MDL 105519 is a potent and selective antagonist of glycine binding to the NMDAreceptor.

YN360245 Pozanicline dihydrochloride 161416-61-1

Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7nM for binding to [3H]cytisine sites. Pozanicline is anα4β2-selectivenAChRagon...

YN360492 Pozanicline 161417-03-4

Pozanicline (ABT-089) selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist atα4β2*nAChRs (Ki=16nM) and shows high selectivity forα6β2* and ...

YN360513 Fanapanel 161605-73-8

Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity againstnMDA; have Ki values of 3.2nM, 100nM, and 8.5μM against quisqualate, kainate, and nMDA, respectively.

YN380103 Rasagiline mesylate 161735-79-1

Rasagiline Mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.

YN360877 Benzamil hydrochloride 161804-20-2

Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+exchanger (NCX) inhibitor (IC50~100nM). Benzamil hydrochloride also is a non-selectiveDeg/epithelial sodium channels (ENaC)blocker, ...

YN360518 Talampanel 161832-65-1

Talampanel (LY300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonis with anti-seizure activity. Talampanel (IVAX) has neuroprotective effects in rodent stroke models. T...

YN322066 α1 adrenoceptor-MO-1 161905-64-2

α1 adrenoceptor-MO-1, an S enantiomer, has affinity atalpha 1 adrenergic receptor, shows alphalytic activity, and possesses analgesic action; more active than R enantiomer.

YN321185 SB-215505 162100-15-4

SB-215505 is a potent and subtype-selective5-HT2Breceptor antagonist with pKi values. of 8.3, 6.77, 7.66 for 5-HT2B, 5-HT2A, 5-HT2C, respectively. SB-215505 increases wakefulness and motor activity in rats.

YN1730012 GR 103691 162408-66-4

GR 103691 is a potent, selectivedopamine D3receptorantagonist with aKivalue of 0.4nM. GR 103691 shows more than 100-fold selectivity for human dopamine human (h)D3over hD4 and hD1sites.

YN320264 WAY-100635 162760-96-5

WAY-100635 is a potent and selective 5-HT1AReceptor antagonist with a pIC50 of 8.87, an apparent pA2of 9.71. WAY-100635 is a potent and selective5-hydroxytryptamine 1A (5-HT1A) receptorantagonist with an IC50 value of...

YN320620 (S)-3,5-DHPG 162870-29-3

(S)-3,5-DHPG is a weak, but selectivegroup I metabotropic glutamate receptors (mGluRs)agonist with Ki values of 0.9 µM and 3.9 µM for mGluR1a and mGluR5a, respectively. (S)-3,5-DHPG exhibits anxiolytic activity in ...

YN380059 Huperzine C 163089-71-2

Huperzine C is an alkaloid isolated fromHuperzia serrate. Huperzine C is anacetylcholinesterase (AChE)inhibotor, with an IC50 of 0.6μM. Huperzine C can be used for the research of Alzheimer’s Disease.

YN484105 MOG (35-55), human 163158-19-8

MOG (35-55), human is a component of CNS myelin. MOG (35-55), human is different from mMOG (35-55) by a proline for serine substitution at position 42. MOG (35-55), human is also immunogenic, but not encephalitogenic, and i...

YN320839 Vilazodone Hydrochloride 163521-08-2

Vilazodone HCl is a selective serotonin reuptake inhibitor (SSRI) and a partial agonist of 5-HT1A receptors, used for the treatment of major depressive disorder.

YN320840 Vilazodone 163521-12-8

Vilazodone is a novel antidepressant having a selective serotonin (5-HT) reuptake inhibitory and 5-HT1A receptor partial agonist activity. The affinity of vilazodone is much higher in the 5-HT reuptake site (Ki=0.1 nM) than in no...