YN481307 GPI-1485 186268-78-0

GPI-1485 (GM1485), a nonimmunosuppressive immunophilin lig and , promotes neurofunctional improvement and neural regeneration following stroke.

YN380303 β-Amyloid (1-20) 186319-68-6

β-Amyloid (1-20) consists of amino acids 1 to 20 of beta amyloid protein.

YN380300 β-Amyloid (1-17) 186319-72-2

β-Amyloid (1-17) is a peptide of β-Amyloid, stabilizes the fibres and plays a role in Aβ fibre formation.

YN322089 5-HT3-In-1 186348-68-5

5-HT3-In-1 is extracted from patent EP0748807A1, compound example 8. It shows5-HT3inhibition activity.

YN484008 β-Amyloid (1-34) 186359-65-9

β-Amyloid (1-34) is a β-Amyloid peptide consists of 34 amino acid.

YN484159 β-Amyloid (1-38), mouse, rat 186359-66-0

β-Amyloid (1-38), mouse, rat is composed of 38 aa (1-38 residues of the Aβ peptide) and is the primary component of the amyloid plaques of Alzheimer’s disease.

YN330195 GPI-1046 186452-09-5

GPI-1046 is a immunophilin lig and without antibiotic action and attenuates ethanol intake in part through the upregulation ofglutamate transporter 1 (GLT1)in PFC and NAc-core. GPI-1046 is an analog of FK506, which is a...

YN320805 LY 344864 racemate 186543-64-6

LY 344864 racemate is a5-HT1Freceptoragonist extracted from patent US 5708187 A.

YN320802 LY 344864 186544-26-3

LY 344864 is a selective receptor agonist with an affinity of 6nM (Ki) at the recently cloned 5-HT1F receptor.

YN420323 2B-(SP) 186901-17-7

2B-(SP) is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3). 2B-(SP) is readily phosphorylated by both the α and β isoforms of GSK-3.

YN321987 Cortistatin-14 186901-48-4

Cortistatin-14, a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 shows anticonvulsive, neuroprotective effect and remarkable anti-in...

YN484176 Axomadol 187219-99-4

Axomadol (EN3324) is a centrally active analgesic agent with opioid agonistic properties and inhibitory effects on the reuptake of monoamines.

YN360215 Flindokalner 187523-35-9

Flindokalner (BMS-204352) is apotassium channelmodulator. Flindokalner is a positive modulator of all neuronalKv7 channelsubtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel(BK...

YN320240 PNU-142633 187665-65-2

PNU-142633 is a high affinity, selective and orally active5-HT1Dreceptoragonist with Kis of 6nM and > 18 000nM for human5-HT1Dreceptor and human 5-HT1Breceptor, respectively. PNU-142633 has anti-migraine efficacy.

YN360505 Imepitoin 188116-07-6

AWD 131-138 is a centrally acting anti-epileptic which crosses the blood brain barrier and is used for the treatment of canine idiopathic epilepsy.

YN483762 NocII 188119-47-3

NocII is an orphan neuropeptide which stimulates locomotion in mice.

YN320296 Frakefamide 188196-22-7

Frakefamide is a potent analgesic that acts as a peripheral activeμ-selective receptoragonist. Frakefamide is unable to penetrate the blood-brain-barrier and enter the central nervous system.

YN480137 Paliroden 188396-77-2

Paliroden is an orally bioactive neurotrophic, non-peptidic compound that activates synthesis of endogenous neurotrophines, used for treatment of Alzheimer's Disease and Parkinson's.

YN370267 MAFP 188404-10-6

MAFP (Methyl Arachidonyl Fluorophosphonate) is an selective, active-site directed and irreversible inhibitor ofcPLA2 and iPLA2. MAFP is also a potent irreversible inhibitor ofan and amide amidase.

YN372598 4-Ethynyl-L-phenylalanine hy... 188640-63-3

4-Ethynyl-L-phenylalanine hydrochloride is a selective, reversible, potent and competitive inhibitor oftryptophan hydroxylase (TPH). 4-Ethynyl-L-phenylalanine hydrochloride is a competitive inhibitor with regard to the substrate tr...