YN360517 Becampanel 188696-80-2

Becampanel (AMP397) is the first competitiveAMPAantagonist and an antiepileptic agent.

YN481661 (5R)-BW-4030W92 189013-61-4

(5R)-BW-4030W92 is the R enantiomer of BW-4030W92. BW-4030W92 is a non-selective, voltage-, and use-dependentsodium channelantagonist.

YN320825 Tegaserod maleate 189188-57-6

Tegaserod Maleate is a hydrogen maleate salt form of tegaserod, which is a 5-HT4 receptor partial agonist and binds with high affinity to 5-HT4 receptors. It has limited affinity for 5-HT1 receptors and no appreciable affinity for ...

YN321797 Endomorphin 1 189388-22-5

Endomorphin 1, a high affinity, highly selective agonist of theμ-opioid receptor, displays reasonable affinities for kappa3binding sites, withKivalue between 20 and 30nM.

YN380296 β-amyloid 1-11 190436-05-6

β-amyloid (1-11) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.

YN1730096 Pramipexole dihydrochloride h... 191217-81-9

Pramipexole 2HCl Monohydrateis a novel non-ergoline dopamine (DA) agonist, used to treat Parkinson's disease.

YN360194 SIB-1553A 191611-89-9

SIB-1553A is an orally bioavailablenicotinic acetylcholine receptors (nAChRs)agonist, with selectivity for β4 subunit-containing nAChRs. SIB-1553A is also a selective neuronal nAChR lig and . SIB-1553A is a cognitive e...

YN320335 CGP71683 hydrochloride 192322-50-2

CGP71683 hydrochloride is a competitiveneuropeptide Y5 receptorantagonist with a Ki of 1.3nM, and shows no obvious activity at Y1 receptor (Ki, >4000nM) and Y2 receptor (Ki, 200nM) in cell membranes.

YN321881 Neuropeptide AF (93-110), H... 192387-38-5

Neuropeptide AF (93-110), Human is anendogenousantiopioid peptide.

YN360066 PPADS tetrasodium 192575-19-2

PPADS tetrasodiuma is a non-selective P2X receptorantagonist. PPADS tetrasodiuma blocks recombinant P2X1, -2, -3, -5 with IC50s ranging from 1 to 2.6μM. PPADS tetrasodiuma blocks native P2Y2-like (IC50~0.9 mM) a...

YN320735 SR144528 192703-06-3

SR144528 is a potent and selectiveCB2 receptorantagonist with a Ki of 0.6nM.

YN373986 L791943 192767-01-4

L791943 is a potent, selectivePhosphodiesterase-4(PDE4) inhibitor with an IC50 of 4.2nM.

YN320748 LY310762 192927-92-7

LY310762 is a 5-HT1D receptor antagonist with Ki of 249nM, having a weaker affinity for 5-HT1B receptor. IC50 value: 249nM (Ki)

YN320949 Capromorelin Tartrate 193273-69-7

Capromorelin Tartrate (CP 424391-18), a member of the growth hormone secretagogue (GHS) class of drugs, is a ghrelin receptor agonist and a novel therapy for stimulation of appetite in dogs with Ki of 7 nM for hGHS...

YN320702 BRL-15572 dihydrochloride 193611-72-2

BRL-15572 is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor.

YN483847 Cortistatin 14, human, rat 193829-96-8

Cortistatin 14, human, rat (CST-14, human, rat), a neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological ac...

YN360100 CP-409092 194098-25-4

CP-409092 is a partial agonist ofGABAAreceptor, with anti-anxiety activity.

YN483831 GaTx2 194665-85-5

GaTx2 is a seletive and a high affinity inhibitor ofClC-2 channelswith a voltage-dependent apparentKDof ∼20 pM. GaTx2 is a peptide toxin inhibitor fromLeiurus quinquestriatus hebraeusvenom. GaTx2 is useful in determining the...

YN320818 R121919 195055-03-9

R121919 (NBI30775) is a potent small-moleculeCRF1receptor antagonist with a Ki of 2 to 5nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types.

YN322096 SB 258719 195199-95-2

SB 258719 is a selective5-HT7receptorantagonist with a pKi of 7.5.