Nintedanib
Cat. No. :YN440409
CAS No. :656247-17-5
Product Name: | Nintedanib |
CAS NO.: | 656247-17-5 |
Chemical Name: | |
Synonyms: | Intedanib |
Molecular Weight: | 539.62 |
Molecular Formula: | C₃₁H₃₃N₅O₄ |
SMILES: | O=C1NC2=CC(C(OC)=O)=CC=C2/C1=C(NC3=CC=C(N(C(CN4CCN(C)CC4)=O)C)C=C3)C5=CC=CC=C5 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3. |
IC50&Target: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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