BO-264
Cat. No. :YN440281
CAS No. :2408648-20-2
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order@ubiochem.com| Product Name: | BO-264 |
| CAS NO.: | 2408648-20-2 |
| Chemical Name: | |
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| Molecular Weight: | 353.38 |
| Molecular Formula: | C₁₈H₁₉N₅O₃ |
| SMILES: | COC1=CC=C(C2=NOC(NC3=NC(N4CCOCC4)=NC=C3)=C2)C=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | BO-264 is a potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3) with IC50 of 188 nM and Kd of 1.5 nM. BO-264 specifically blocks the function of FGFR3-TACC3 fusion protein. BO-264 induces SAC-dependent mitotic arrest, apoptosis and DNA damage with antitumor activities. |
| IC50&Target: | |
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