Alofanib
Cat. No. :YN440369
CAS No. :1612888-66-0
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5mg
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Product Name: | Alofanib |
CAS NO.: | 1612888-66-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 413.40 |
Molecular Formula: | C₁₉H₁₅N₃O₆S |
SMILES: | O=C(O)C1=CC=CC(S(=O)(NC2=CC(C3=CC=CN=C3)=C(C)C=C2[N+]([O-])=O)=O)=C1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Alofanib(RPT835) is a novel selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect with IC50 <10 nM on FGF2-induced phoshphorylation of FRS2a in KATO III cells. It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding. |
IC50&Target: | |
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References: |
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