TG 100801
Cat. No. :YN440049
CAS No. :867331-82-6
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order@ubiochem.com| Product Name: | TG 100801 |
| CAS NO.: | 867331-82-6 |
| Chemical Name: | |
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| Molecular Weight: | 580.08 |
| Molecular Formula: | C₃₃H₃₀ClN₅O₃ |
| SMILES: | O=C(C1=CC=CC=C1)OC2=CC=C(Cl)C(C3=CC(C)=C(N=C(NC(C=C4)=CC=C4OCCN5CCCC5)N=N6)C6=C3)=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | TG 100801 is a prodrug that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibitsreceptor tyrosine kinases and Src kinases; hasIC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively. |
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| References: |
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