Orantinib
Cat. No. :YN440102
CAS No. :252916-29-3
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Product Name: | Orantinib |
CAS NO.: | 252916-29-3 |
Chemical Name: | |
Synonyms: | NSC 702827 |
Molecular Weight: | 310.35 |
Molecular Formula: | C₁₈H₁₈N₂O₃ |
SMILES: | CC1=C(/C=C2C3=CC=CC=C3NC/2=O)NC(C)=C1CCC(O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Orantinib (TSU-68, SU6668) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM in a cell-free assay, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2 does not inhibit EGFR. Phase 3. |
IC50&Target: | |
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References: |
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