H3B-6527
Cat. No. :YN440014
CAS No. :1702259-66-2
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Product Name: | H3B-6527 |
CAS NO.: | 1702259-66-2 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 629.54 |
Molecular Formula: | C₂₉H₃₄Cl₂N₈O₄ |
SMILES: | C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | H3B-6527 is a highly selective covalent FGFR4 inhibitor with an IC50 value of <1.2 nM and at least 250-fold selectivity over FGFR1-3 (IC50 values of 320, 1,290 and 1,060 nM respectively). |
IC50&Target: | |
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In Vivo: | |
Clinical Trial: | |
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References: |
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