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H3B-6527

Cat. No. :YN440014

  • CAS No. :1702259-66-2

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    • Products Infomation
    • Biological Activity
    • Reference
    • Product Name:H3B-6527
      CAS NO.:1702259-66-2
      Chemical Name:
      Synonyms:
      Molecular Weight:629.54
      Molecular Formula:C₂₉H₃₄Cl₂N₈O₄
      SMILES:C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:H3B-6527 is a highly selective covalent FGFR4 inhibitor with an IC50 value of <1.2 nM and at least 250-fold selectivity over FGFR1-3 (IC50 values of 320, 1,290 and 1,060 nM respectively).
      IC50&Target:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
      References:
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