Derazantinib
Cat. No. :YN440396
CAS No. :1234356-69-4
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order@ubiochem.com| Product Name: | Derazantinib |
| CAS NO.: | 1234356-69-4 |
| Chemical Name: | |
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| Molecular Weight: | 468.57 |
| Molecular Formula: | C₂₉H₂₉FN₄O |
| SMILES: | COCCNCCC1=CC(NC2=NC=C3C[C@@H](C4=CC=CC=C4F)C5=CC=CC=C5C3=N2)=CC=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Derazantinib(ARQ-087) is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3, showing lower potency for FGFR4 (IC50=34 nM). It also inhibits RET, DDR2, PDGFRβ, VEGFR and KIT. |
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