Sulfatinib
Cat. No. :YN440202
CAS No. :1308672-74-3
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order@ubiochem.com| Product Name: | Sulfatinib |
| CAS NO.: | 1308672-74-3 |
| Chemical Name: | |
| Synonyms: | HMPL-012, Sufatinib, Surfatinib |
| Molecular Weight: | 480.58 |
| Molecular Formula: | C₂₄H₂₈N₆O₃S |
| SMILES: | O=S(CC1=CC=CC(NC2=NC=CC(OC3=CC4=C(NC(C)=C4)C=C3)=N2)=C1)(NCCN(C)C)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Sulfatinib is a potent and highly selective tyrosine kinase inhibitor against VEGFR1, VEGFR2, VEGFR3, FGFR1 and CSF1R with IC50 of 2 nM, 24 nM, 1 nM, 15 nM and 4 nM, respectively. Sulfatinib shows encouraging antitumor activity and manageable toxicities in patients with advanced NETs. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
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