LY2874455
Cat. No. :YN440263
CAS No. :1254473-64-7
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order@ubiochem.com| Product Name: | LY2874455 |
| CAS NO.: | 1254473-64-7 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 444.31 |
| Molecular Formula: | C₂₁H₁₉Cl₂N₅O₂ |
| SMILES: | ClC1=CN=CC(Cl)=C1[C@@H](C)OC2=CC=C(NN=C3/C=C/C4=CN(CCO)N=C4)C3=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM, 2.6 nM, 6.4 nM, and 6 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively, and also inhibits VEGFR2 activity with IC50 of 7 nM. Phase 1. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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