Infigratinib
Cat. No. :YN440265
CAS No. :872511-34-7
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order@ubiochem.com| Product Name: | Infigratinib |
| CAS NO.: | 872511-34-7 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 560.48 |
| Molecular Formula: | C₂₆H₃₁Cl₂N₇O₃ |
| SMILES: | ClC1=C(C(Cl)=C(C=C1OC)OC)NC(N(C2=CC(NC3=CC=C(C=C3)N4CCN(CC4)CC)=NC=N2)C)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM in cell-free assays, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2. |
| IC50&Target: | |
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| References: |
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