Lucitanib
Cat. No. :YN440315
CAS No. :1058137-23-7
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5mg
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10mg
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Product Name: | Lucitanib |
CAS NO.: | 1058137-23-7 |
Chemical Name: | |
Synonyms: | AL3810 |
Molecular Weight: | 443.49 |
Molecular Formula: | C₂₆H₂₅N₃O₄ |
SMILES: | O=C(NC)C1=CC=CC2=C1C=CC(OC3=CC=NC4=CC(OCC5(N)CC5)=C(OC)C=C43)=C2 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Lucitanib (E-3810, AL3810) hydrochloride is a dual inhibitor of Vascular endothelial growth factor receptor (VEGFR) and Fibroblast growth factor receptor (FGFR). Lucitanib hydrochloride (E-3810, AL3810) potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 with IC50 of 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively. |
IC50&Target: | |
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In Vivo: | |
Clinical Trial: | |
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References: |
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