Gilteritinib
Cat. No. :YN440210
CAS No. :1254053-43-4
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Product Name: | Gilteritinib |
CAS NO.: | 1254053-43-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 552.71 |
Molecular Formula: | C₂₉H₄₄N₈O₃ |
SMILES: | NC(C1=NC(CC)=C(NC2CCOCC2)N=C1NC3=CC(OC)=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Gilteritinib(ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. It inhibits FLT3 at an IC50 value that was approximately 800-fold more potent than the concentration required to inhibit c-KIT (230 nM). |
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