CHIR-124
Cat. No. :YN440257
CAS No. :405168-58-3
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order@ubiochem.com| Product Name: | CHIR-124 |
| CAS NO.: | 405168-58-3 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 419.91 |
| Molecular Formula: | C₂₃H₂₂ClN₅O |
| SMILES: | ClC1=CC2=C(NC(C(C3=NC4=C(C=CC=C4)N3)=C2N[C@@H]5CN6CCC5CC6)=O)C=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | CHIR-124 is a novel and potent Chk1 inhibitor with IC50 of 0.3 nM in a cell-free assay. It shows 2,000-fold selectivity against Chk2, 500- to 5,000-fold less activity against CDK2/4 and Cdc2. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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