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G-749

Cat. No. :YN440205

  • CAS No. :1457983-28-6

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    • Products Infomation
    • Biological Activity
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    • Product Name:G-749
      CAS NO.:1457983-28-6
      Chemical Name:
      Synonyms:
      Molecular Weight:521.41
      Molecular Formula:C₂₅H₂₅BrN₆O₂
      SMILES:O=C1C2=C(N=C(NC3CCN(C)CC3)N=C2NC4=CC=C(OC5=CC=CC=C5)C=C4)C(Br)=CN1
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases.
      IC50&Target:
      In Vitro:
      In Vivo:
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      Solvent & Solubility:
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