CCT241736
Cat. No. :YN440373
CAS No. :1402709-93-6
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order@ubiochem.com| Product Name: | CCT241736 |
| CAS NO.: | 1402709-93-6 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 456.37 |
| Molecular Formula: | C₂₂H₂₃Cl₂N₇ |
| SMILES: | CC1=NN(C)C=C1C2=NC3=C(N4CCN(CC5=CC=C(Cl)C=C5)CC4)C(Cl)=CN=C3N2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | CCT241736 is a potent and orally bioavailable dualFLT3 and Aurora kinaseinhibitor, which inhibits Aurora kinases (Aurora-AKd, 7.5nM,IC50, 38nM; Aurora-BKd, 48nM), FLT3 kinase (Kd, 6.2nM), and FLT3 mutants including FLT3-ITD (Kd, 38nM) and FLT3(D835Y) (Kd, 14nM). |
| IC50&Target: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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