UNC2025 hydrochloride
Cat. No. :YN440207
CAS No. :2070015-17-5
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5mg
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order@ubiochem.com| Product Name: | UNC2025 hydrochloride |
| CAS NO.: | 2070015-17-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 513.12 |
| Molecular Formula: | C₂₈H₄₁ClN₆O |
| SMILES: | CN1CCN(CC2=CC=C(C3=CN([C@@H]4CC[C@@H](O)CC4)C5=NC(NCCCC)=NC=C53)C=C2)CC1.[H]Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | UNC2025 hydrochloride is a potent and highly orally activeMer/Flt3inhibitor with IC50 values of 0.74nM and 0.8nM, respectively. UNC2025 hydrochloride is >45-fold selectivity for MERTK relative to Axl (IC50= 122nM;Ki= 13.3nM). UNC2025 hydrochloride exhibits an excellent PK properties, and can be used for the investigation of acute leukemia. |
| IC50&Target: | |
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