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Gilteritinib

Cat. No. :YN440210

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    • Products Infomation
    • Biological Activity
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    • Product Name:Gilteritinib
      CAS NO.:1254053-43-4
      Chemical Name:
      Synonyms:
      Molecular Weight:552.71
      Molecular Formula:C₂₉H₄₄N₈O₃
      SMILES:NC(C1=NC(CC)=C(NC2CCOCC2)N=C1NC3=CC(OC)=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)=O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Gilteritinib(ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. It inhibits FLT3 at an IC50 value that was approximately 800-fold more potent than the concentration required to inhibit c-KIT (230 nM).
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