YN251360 Tosufloxacin tosylate hydrate 1400591-39-0

Tosufloxacin is a fluoroquinolone antibiotic that is used to treat susceptible infections.

YN250826 ACHN-975 TFA 1410809-37-8

ACHN-975 TFA is a selectiveLpxCinhibitor and exhibits a subnanomolar LpxC inhibitory activity. ACHN-975 TFA is against a wide range of gram-negative bacterias with lowMICvalues (≤1 μg/mL).

YN250464 CDK9-IN-1 1415559-43-1

CDK9-IN-1 is a novel, selectiveCDK9inhibitor for the treatment of HIV infection, with an IC50 of 39nM for CDK9/CycT1, extracted from reference, compound 87.

YN372493 (±)-BI-D 1416258-16-6

(±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.

YN250520 ML188 1417700-13-0

ML188, a first in class probe, is a selective non-covalent SARS-CoV3CLproinhibitor with an IC50 of 1.5μM. Antiviral activity.

YN371682 Mefentrifluconazole 1417782-03-6

Mefentrifluconazole is a novel azole derivative and used as an agrochemical broad-spectrumantifungal agent. Mefentrifluconazole is a potent, selective and orally active fungalCYP51(Kd= 0.5nM) inhibitor, but shows less inhibitory ...

YN483360 Fumonisin B3 1422359-85-0

Fumonisin B3 is a mycotoxin derived fromfusariumfungi, a member of fumonisins.

YN250181 Ziresovir 1422500-60-4

Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein inhibitor. Ziresovir shows anti-RSV activity (EC50=3nM) and highlights p...

YN251853 Tat-beclin 1 1423821-88-8

Tat-beclin 1, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer ofautophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of p...

YN360683 (+)-SJ733 1424799-20-1

(+)-SJ733 is ananti-malariaagent which can also inhibitNa+-ATPase PfATP4.

YN372283 Grazoprevir sodium salt 1425038-27-2

Grazoprevir sodium salt (MK-5172 sodium salt) is a selective inhibitor ofHepatitis C virus NS3/4aprotease with broad activity across genotypes and resistant variants, with Kis of 0.01nM (gt1b), 0.01nM (gt1a), 0.08nM (gt2a), 0.1...

YN250078 KIN1148 1428729-56-9

KIN1148, a small-moleculeIRF3agonist, is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy.

YN250154 RIG-1 modulator 1 1428729-63-8

RIG-1 modulator 1 is an anti-viral compound which can be useful for the treatment of viral infections includinginfluenza virus,HBV,HCV and HIVextracted from patent WO 2015172099 A1.

YN250238 Retro-2 cycl 1429192-00-6

Retro-2 cycl (RN 1-001) is a dihydroquinazolinone (DHQZ) inhibitor of retrograde trafficking. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus with IC50s of 54μM and 160μM, respectively. Antiviral age...

YN481406 (S)-Tedizolid 1431699-67-0

(S)-Tedizolid is the S-enantiomer of Tedizolid. Tedizolid is a novel oxazolidinone with activity against Gram-positive pathogens. (S)-Tedizolid is the less active isomer.

YN420326 BF738735 1436383-95-7

BF738735 is a phosphatidylinositol 4-kinase III beta (PI4KIIIβ) inhibitor with an IC50 of 5.7nM.

YN250304 Zidebactam 1436861-97-0

Zidebactam (WCK-5107) is a potentβ-lactamase inhibitor. Zidebactam also is apenicillin-binding protein2 (PBP2)inhibitor with an IC50 of 0.26 μg/mL.

YN250647 Ledipasvir (acetone) 1441674-54-9

Ledipasvir (GS-5885) acetone is the active ingredient of Ledipasvir. Ledipasvir is a potent, oral active inhibitor of the hepatitis C virus (HCV) NS5A with EC50 of 31 pM and 4 pM against GT1a and GT1b replicon, re...

YN250209 GSK2200150A 1443138-53-1

GSK2200150A, identified by high-throughput screening (HTS) campaign, is an anti-tuberculosis (TB) agent.

YN250352 Divin 1443321-11-6

Divin, a potent chelator of iron, is a potent inhibitor ofbacterial cell divisionwith bacteriostatic effect inGram-negative and Gram-positive bacteria. Divin disrupts the assembly of late division proteins, reduces peptidoglycan remodel...