YN250657 GSK2838232 1443460-91-0

GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates, extracted from patent WO/2013090664A1, compound51.

YN251796 Aviptadil acetate 1444827-29-5

Aviptadil acetate is an analogvasoactive intestinal polypeptide (VIP)with potentvasodilatoryeffects. Aviptadil acetate induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil aceta...

YN250433 ALS-8112 1445379-92-9

ALS-8112 is a potent and selective respiratory syncytial virus (RSV) polymerase inhibitor. The 5'-triphosphate form of ALS-8112 inhibits RSV polymerase with an IC50 of 0.02μM.

YN250434 Lumicitabine 1445385-02-3

Lumicitabine (ALS-008176) is an inhibitor of the respiratory syncytial virus (RSV) polymerase.

YN250347 NVR 3-778 1445790-55-5

NVR 3-778 is a first-in-Class and oral bioavailableHBV CAM(capsid assembly modulator) belonging to the SBA (sulfamoylbenzamide) class, with anti-HBV activity.

YN250010 9-Propenyladenine 1446486-33-4

9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase inhibitors, which block reverse transcriptase, a crucial virus enzyme in H...

YN371006 IHVR-19029 1447464-73-4

IHVR-19029 is a potent endoplasmic reticulum (ER)α-glucosidases I and IIinhibitor, with an IC50 of 0.48μM for ER a-glucosidase I. IHVR-19029 efficiently blocks the replication of several hemorrhagic fever viruses, such ...

YN420087 UCT943 1450666-80-4

UCT943 is a next-generationPlasmodium falciparumPI4Kinhibitor. UCT943 inhibits theP. vivaxPI4K (PvPI4K) enzyme with an IC50 of 23nM.

YN250226 LHF-535 1450929-77-7

LHF-535 is an antiviral agent extracted from patent WO2013123215A2, Compound 38, has EC50s of <1μM, <1μM, <1μM, and 1-10μM for Lassa, Machupo, Junin, and VSVg virus, respectively.

YN250393 LDC4297 1453834-21-3

LDC4297 is a novel CDK7 inhibitor (IC50=0.13±0.06 nM for CDK7 versus IC50s between 10 nM and 10,000 nM for all other analyzed CDKs).

YN250011 (Z)-9-Propenyladenine 1464851-21-5

(Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucial v...

YN250270 Durlobactam sodium salt 1467157-21-6

Durlobactam sodium salt (ETX2514) is a broad-spectrumβ-lactamaseinhibitor with IC50s of 4, 14 and 190nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-n...

YN440417 QL47 1469988-75-7

QL47, a broad-spectrumantiviralagent, inhibits dengue virus and other RNA viruses. QL47 selectively inhibits eukaryotic translation. QL47 is a potent covalent inhibitor ofBTKwith an IC50 of 7nM .

YN440216 Hck-IN-1 1473404-51-1

Hck-IN-1 (compound B9), a diphenylpyrazolo compound, is a selectiveNef-dependent Hckinhibitor with IC50s of 2.8μM, >20μM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wideHIV-1 Nefantagonists ...

YN250183 NITD-349 1473450-62-2

NITD-349 is anMmpL3inhibitor that shows highly potent anti-mycobacterial activity withMIC50 of 23nM against virulentMycobacterium tuberculosisH37Rv.

YN251271 Cefalonium hydrate 1486466-27-6

Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

YN250182 BM635 1493762-74-5

BM635 is aMmpL3inhibitor with outst and ing anti-mycobacterial activity. BM635 has anMIC50 of 0.12μM againstM. tuberculosisH37Rv.

YN250816 TBA-7371 1494675-86-3

TBA-7371 is a potent, noncovalentDprE1inhibitor. TBA-7371 has potent antitubercular activity.

YN250648 Ledipasvir D-tartrate 1502654-87-6

Ledipasvir D-tartrate is an inhibitor of thehepatitis C virus NS5A, withEC50values of 34 pM against GT1a and 4 pM against GT1b replicon.

YN420143 KDU691 1513879-19-0

KDU691 is a Plasmodium PI4K -specific inhibitor with IC50 values of 0.18 μM and 0.061 μM against hypnozoite forms and liver schizontsm, respectively.