YN420257 BQR-695 1513879-21-4

BQR695 is a quinoxaline that displays sub-micromolar potency against human PI4KIIIβ (IC50~90 nM).

YN250811 BRD3308 1550053-02-5

BRD3308 is a potant and highly selective inhibitor of HDAC3 with IC50 of 54 nM, 1.26 μM and 1.34 μM for HDAC3, HDAC1 and HDAC2, respectively. BRD3308 activates HIV-1 transcription. BRD3308 suppresse...

YN250365 Pseudouridimycin 1566586-52-4

Pseudouridimycin (PUM), an antibiotic, is a selective bacterialRNA polymerase (RNAP)inhibitor. Pseudouridimycin is a C-nucleoside analogue that is effective against both Gram-negative and Gram-positive bacteria.

YN250218 JNJ-632 1572510-42-9

JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator (CAM).

YN250210 AB-423 1572510-80-5

AB-423 is an inhibitor ofHBV capsidassembly, and potent inhibits HBV replication with EC50/EC90of 0.08-0.27μM/0.33-1.32μM in cells.

YN250785 Chitinase-IN-1 1579991-61-9

Chitinase-IN-1 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20 uM compound concentration's inhibitory percentage are 75%/67% for chitinase/N- acetyl-hexosaminidase respectively.

YN250320 Inz-5 1585214-21-6

Inz-5 is a fungal-selectivemitochondrial cytochrome bc1inhibitor. Inz-5 impairs fungal virulence and prevents the evolution of drug resistance.

YN251809 Peptide T TFA 1610056-01-3

Peptide T (TFA) is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a lig and for theCD4receptor and prevents binding ofHIVto the CD4 receptor.

YN420042 KDU731 1610610-48-4

KDU731, an orally activeC. parvumPI4Kinhibitor with an IC50 value of 25nM, blocksCryptosporidiuminfection in vitro and in vivo. KDU731 is a promising drug c and idate for the treatment of diarrhea caused byCryptosporidium a...

YN372460 Bictegravir 1611493-60-7

Bictegravir is a novel, potent, once-daily, unboosted inhibitor of HIV-1 integrase.

YN250417 HIV-1 inhibitor-3 1612841-22-1

HIV-1 inhibitor-3 is aHIVinfection inhibitor extracted from patent US2018360927.

YN250327 NITD-916 1614262-83-7

NITD-916, a 4-hydroxy-2-pyridone derivative, is an orally active and highly lipophilicmycobacterial enoyl reductase InhAinhibitor with an IC50 of 570nM. NITD-916 forms a ternary complex withInhA and NADH to block acces...

YN250031 DprE1-IN-2 1615713-87-5

DprE1-IN-2 (compound 18) is a potentDprE1inhibitor with an IC50 of 28nM. DprE1-IN-2 has antituberculosis effect.

YN250525 Oxazosulfyl 1616678-32-0

Oxazosulfyl is a potent agriculturalfungicide. Oxazosulfyl can be used as an insecticide against major rice pests.

YN250777 Zoliflodacin 1620458-09-4

Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrionebacterial DNA gyrase/topoisomeraseinhibitor. Zoliflodacin has potentin vitroantibacterial activity against Gram-positive and Gram-negative organisms, includingS....

YN250404 AN7973 1620899-32-2

AN7973 is the 6-carboxamide benzoxaborole, blocks intracellularparasitedevelopment and inhibitsCryptosporidiumgrowth. AN7973 is orally active, possesses favorable safety, stability, and PK parameters, and is an exciting drug c ...

YN250653 PSI-7409 tetrasodium 1621884-22-7

PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), inhibitingHCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B...

YN250337 Pimodivir 1629869-44-8

Pimodivir (VX-787) is an orally bioavailable inhibitor ofinfluenza A virus polymerasesthrough interaction with the viralPB2subunit.

YN250155 Rezafungin acetate 1631754-41-0

Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinoc and in. Rezafungin acetate shows potent antifungal activity againstC and ida spp.,Aspergillus spp., and Pneumocystis spp..

YN250375 ML303 1638211-04-7

ML303 is a pyrazolopyridineinfluenza virus nonstructural protein 1 (NS1)antagonist (IC90= 155nM), with an EC50 of 0.7μM for Influenza A virus H1N1.