YN370436 HIV-1 integrase inhibitor 3 1638504-56-9

HIV-1 integrase inhibitor 3 is aHIV-1 integrase str and transfer(INST) inhibitor with an IC50 of 2.7nM.

YN370437 HIV-1 integrase inhibitor 4 1638504-66-1

HIV-1 integrase inhibitor 4 is aHIV-1 integrase str and transfer(INST) inhibitor with an IC50 of 3.7nM.

YN250449 LolCDE-IN-1 1639933-78-0

LolCDE-IN-1 is an inhibitor of theLol proteins (LolCDE) complex, with antibacterial activity.

YN371170 hDHODH-IN-4 1644156-56-8

hDHODH-IN-4 is a potent hum and ihydroorotate dehydrogenase (DHODH)inhibitor, with apIC50 of 7.8 for human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication, with apMIC50 of 8.8.

YN371597 hDHODH-IN-3 1644156-80-8

hDHODH-IN-3 (compound 21d) is ahuman dihydroorotate dehydrogenase (HsDHODH)inhibitor, inhibits measles virus replication with apMIC50 value of 8.6.

YN250338 MMV008138 1679333-73-3

MMV008138 is a species-selectiveIspD (enzyme 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase)-targeting antimalarial agent, with an IC50 of 44nM forPfIspD(P. falciparumIspD). MMV008138 inhibits the growth ofP. fa...

YN250215 ZINC03129319 1777807-64-3

ZINC03129319 is a dengue virus (DENV)NS2B-NS3 proteaseinhibitor extracted from patent US20150141521A1, has inhibition constants (Ki1) of 92μM and Ki3of 20μM.

YN250824 Contezolid acefosamil 1807497-11-5

Contezolid acefosamil (MRX-4) is the orally active prodrug of the active antimicrobial metabolite Contezolid (MRX-I), an oxazolidinone which shows potent in vitro activity against various multidrug-resistant Gram-positive bacteria...

YN250103 Remdesivir 1809249-37-3

Remdesivir (GS-5734), a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.

YN360891 β-Cyfluthrin 1820573-27-0

β-Cyfluthrin (beta-Cyfluthrin) is a type II syntheticpyrethroid and also an active ingredient of many insecticide products used for pestsin agriculture. β-Cyfluthrin is aneurotoxicant and affects calcium concentration in nervous ti...

YN330101 CU-T12-9 1821387-73-8

CU-T12-9 is a specificTLR1/2agonist withEC50of 52.9nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, no...

YN250804 Ribocil-C 1825355-56-3

Ribocil-C is a highly selective inhibitor ofbacterial riboflavin riboswitches.

YN251912 Danofloxacin-d3 1825377-28-3

Danofloxacin-d3 is deuterium labeled Danofloxacin. Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against mostGram-negative and Gram-positive...

YN330152 TH1020 1841460-82-9

TH1020 is a potent and selectivetoll-like receptor 5 (TLR5)/flagellin complexantagonist with an IC50 of 0.85μM. TH1020 inhbits flagellin-inducedTLR5signaling. TH1020 is inactive against TLR2, TLR3, TLR4, TLR7 ...

YN330350 Chloroquine D5 1854126-41-2

Chloroquine D5 is deuterium labeled Chloroquine. Chloroquine is anantimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is anautophagy and toll-like receptors (TLRs)inhibitor....

YN250511 TH1217 1862212-48-3

TH1217 (ZINC1775962367) is a potent and selectivedCTPase pyrophosphatase 1 (dCTPase)inhibitor, with an IC50 of 47nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modula...

YN420005 PI4KIIIbeta-IN-10 1881233-39-1

PI4KIIIbeta-IN-10 is a potent PI4KIIIβ inhibitor with an IC50 of 3.6nM.

YN250828 KIN1408 1903800-11-2

KIN1408 is an agonist of theRIG-1-like receptor (RLR) pathway and exhibits a broad-spectrum antiviral activity. KIN1408 exhibits activity againstHCV,influenza A,dengue virus 2,Ebola,Nipah, and Lassa viruses.

YN372631 Remdesivir nucleoside monopho... 1911578-74-9

Remdesivir nucleoside monophosphate is a metabolite of Remdesivir. Remdesivir is a nucleoside analogue with effective antiviral activity against SARS-CoV and MERS-CoV.

YN481054 Anti-virus agent 1 1911578-83-0

Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734 (HY-104077; Remdesivir), has potentantiviralactivity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV).