YN371599 6-Raloxifene-β-D-glucopyran... 334758-18-8

6-Raloxifene-β-D-glucopyranoside, a derivative of Raloxifene, is a benzothiophene glucuronidated at the 6' postion. 6-Raloxifene-β-D-glucopyranoside is a selective and orally activeestrogen receptorantagonist. 6-Raloxifene-β-D-...

YN481241 4'-Raloxifene-β-D-glucopyra... 334758-19-9

4'-Raloxifene-β-D-glucopyranoside, a metabolite of Raloxifene, is a benzothiophene glucuronidated at the 4' postion. 4'-Raloxifene-β-D-glucopyranoside is a selective and orally activeestrogen receptorantagonist. 4'-Raloxifene-β-D...

YN483129 Raddeanoside 20 335354-79-5

Raddeanoside 20 is a triterpenoid isolated from the rhizome ofAnemone raddeana. Raddeanoside 20 can suppresse superoxide generation.

YN1720015 Tonapofylline 340021-17-2

Tonapofylline (BG 9928) is an orally active and selectiveadenosine A1receptorantagonist with aKiof 7.4nM for human adenosine A1receptor (hA1), which displays 915-fold selectivity versus human adenosine A2A receptor and 12-fold...

YN483466 Araloside V 340963-86-2

Araloside V (Congmunoside V) is a triterpenoid saponin isolated fromAralia elata.

YN480287 Alagebrium chloride 341028-37-3

Alagebrium chloride is anadvanced glycation end product(AGE) inhibitor.

YN320867 Velneperit 342577-38-2

Velneperit (S-2367) is a novel neuropeptide Y (NPY) Y5 receptor antagonist.

YN371154 Palatinose hydrate 343336-76-5

Palatinose hydrate is an endogenous metabolite.

YN360038 Lesogaberan 344413-67-8

Lesogaberan (AZD-3355) is a potent and selective GABAB receptoragonist with an EC50 of 8.6nM for human recombinant GABAB receptors. Binding affinity (Kis) of 5.1nM and 1.4μM for rat brain GABAB and GABAA...

YN484062 TfR-T12 344618-30-0

TfR-T12 is a BBB-penetratedtransferrin receptor (TfR)binding peptide, displaying a binding affinity in thenM range.

YN482747 Araloside X 344911-90-6

Araloside X (Congmunoside X) is a triterpenoid saponin isolated fromAralia elata.

YN481208 Atorvastatin methyl ester 345891-62-5

Atorvastatin methyl ester (Compound 2a) is a methyl esterified derivative of Atorvastatin. Atorvastatin methyl ester inhibits the 9-cis-RA-induced Gal4 reporter activity more strongly than Atorvastatin.

YN320206 DC260126 346692-04-4

DC260126 is a potent antagonist ofGPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca2+elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50: 6.28, 5.96, 7.07, 4.58μM...

YN320928 Fedovapagon 347887-36-9

Fedovapagon is a selectivevasopressin V2 receptor (V2R)agonist with an EC50 of 24nM, which is being developed for the treatment of nocturia.

YN321261 GSK137647A 349085-82-1

GSK137647A is a selective FFA4 agonist, with pEC50 of 6.3, 6.2, and 6.1 for human, Mouse and Rat FFA4, respectively.

YN370403 Inosine 5'-monophosphate diso... 352195-40-5

Inosine 5'-monophosphate disodium salt hydrate is an endogenous metabolite.

YN480268 Eprotirome 355129-15-6

Eprotirome (KB2115) is a liver-selective agonist of thyroid hormone receptor (TR). Eprotirome is investigated for the potential treatment of dyslipidemias and obesity.

YN321867 [Ala17]-MCH 359784-84-2

[Ala17]-MCH, a MCH analogue (HY-P1525A), is a selective lig and forMCHR1(Ki=0.16nM) over MCHR2(Ki=34nM). [Eu3+chelate-labeled [Ala17]-MCH shows high affnity for MCHR1(Kd=0.37nM) while has little demonstrab...

YN370250 Saxagliptin 361442-04-8

Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.

YN320914 (±)-Ibipinabant 362519-49-1

(±)-Ibipinabant ((±)-SLV319) is the racemate of SLV319. (±)-Ibipinabant ((±)-SLV319) is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with an IC50 of 22nM.