YN484263 Hydrocarbon chain derivative ... 300762-25-8

Hydrocarbon chain derivative 1 is an active compound, with inhibitory activities against lipid synthesis.

YN250630 Dynasore 304448-55-3

Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM in a cell-free assay, also inhibits the mitochondrial dynamin Drp1, with no effect against other small...

YN321283 GW-1100 306974-70-9

GW-1100 is a selectiveGPR40antagonist with apIC50 of 6.9. GW1100 acts as a GPR40 inverse agonist.

YN1720021 GRA Ex-25 307983-31-9

GRA Ex-25 is an inhibitor ofglucagon receptor, with IC50 of 56 and 55nM for rat and human glucagon receptors, respectively.

YN1720006 NNC-0640 307986-98-7

NNC-0640 is a potenthuman G-protein-coupled glucagon receptor (GCGR)negative allosteric modulator (NAM) with an IC50 of 69.2nM.

YN480388 KL001 309928-48-1

KL001 is a first-in-classcryptochrome(CRY, a flavoproteins that are sensitive to blue light, and is involved in the circadian rhythms of plants and animals) stabilizer which specifically interacts with CRY1 and CRY2. KL00...

YN480639 MID-1 312608-54-1

MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradati...

YN320300 THIQ 312637-48-2

THIQ is the first selective agonist of themelanocortin-4 receptor (MC4R), with high affinity and potency for hMC4R (IC50=1.2nM,EC50=2.1nM) and rMC4R (IC50=0.6nM,EC50=2.9nM). THIQ maintains low potency at MC...

YN372977 2'-Deoxyguanosine monohydrate 312693-72-4

2'-Deoxyguanosine monohydrate is an endogenous metabolite.

YN480603 CID 1375606 313493-80-0

CID 1375606 is a surrogate agonist of orphan G protein-coupled receptorGPR27.

YN360222 PD-118057 313674-97-4

PD-118057 is ahuman ether-a-go-go-related gene (hERG) channelactivator that does not cause hERG blockade.

YN280022 GW 501516 317318-70-0

GW501516 is a effective and highly specifc PPARβ/δ agonist

YN290301 GW0742 317318-84-6

GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ.

YN480960 SKF-34288 hydrochloride 320386-54-7

SKF-34288 hydrochloride (3-Mercaptopicolinic acid) is a phosphoenolpyruvate carboxykinase (PEPCK) inhibitor. SKF-34288 hydrochloride is a potent hypoglycemic agent via inhibition of glucose synthesis through the specific inhibit...

YN250258 BLT-1 321673-30-7

BLT-1, a thiosemicarbazone copper chelator, is a selectivescavenger receptor B, type 1 (SR-BI)inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1...

YN320185 NPS-2143 hydrochloride 324523-20-8

NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potentcalcium ion-sensing receptor (CaSR)antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increase...

YN321887 tcY-NH2 327177-34-4

tcY-NH2 is a selective ratPAR4antagonist peptide. tcY-NH2 inhibits thrombin- and AY-NH2-induced rat platelet aggregation.

YN370105 Rbin-1 328023-11-6

Rbin-1(ribozinoindole-1) is a potent chemical inhibitor of eukaryotic ribosome assembly. It inhibits recombinant full-length Mdn1's ATPase activity in vitro.

YN320977 MK-0557 328232-95-7

MK-0557 is a highly selective, orally available neuropeptideY5receptor antagonist with a Ki of 1.6nM.

YN480886 Maltoheptaose hydrate 331748-09-5

Maltoheptaose hydrate is an activator ofphosphorylase Bto prepare heptulose-2-phosphate. Maltoheptaose hydrate is a maltooligosaccharide contanins seven glucose units.