Chemical structure
Cat.No.
Product Name
CAS no.
Target
AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.
HNGF6A is a humanin analogue. HNGF6A increases glucose-stimulated insulin secretion and glucose metabolism, and has the potential for diabetes research. HNGF6A inhibits ofROSproduction during oxidative stress. HNGF...
YN310264 SRT 2104 1093403-33-8
SRT2104 (GSK2245840) is a selective SIRT1 activator involved in the regulation of energy homeostasis. Phase 2.
YN440280 I-OMe-Tyrphostin AG 538 1094048-77-7
I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor ofIGF-1R(insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cyto...
YN360629 (3R,5R)-Rosuvastatin 1094100-06-7
(3R,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoAreductase inhibitor with an IC50 of 11nM. Rosuvastatin potently blockshuman ether-a-go-go related gene (hERG)current wit...
CCX140 (CCX140-B) is a potentCCR2antagonist.
YN370292 LY2562175 1103500-20-4
LY2562175 is a potent and selectiveFXRagonist, with an EC50 of 193nM.
MK-4256 is a potent and selectiveSSTR3antagonist with IC50s of 0.66nM and 0.36nM in human and mouse receptor binding assays, respectively.
YN320419 SNT-207858 free base 1104662-66-9
SNT207858 free base is a selective, blood brain barrier penetrating, potent and orally activemelanocortin-4(MC-4)receptorantagonist. SNT207858 free base has an IC50 of 22nM (binding) and 11nM (function) on the MC-4 recepto...
YN481209 Atorvastatin 3-Deoxyhept-2E... 1105067-93-3
Atorvastatin 3-Deoxyhept-2E-Enoic Acid ((2E)-2,3-Dehydroxy Atorvastatin) is an impurity of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
YN371225 PF-04620110 1109276-89-2
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
YN360642 Bexagliflozin 1118567-05-7
Bexagliflozin (EGT1442) is a potent and selectivesodium glucose co-transporter 2 (SGLT2)inhibitor, with IC50s of 2nM and 5.6μM for human SGLT2 and SGLT1, respectively. Bexagliflozin can be used for the research o...
YN1720026 GLP-1(7-36), amide acetate 1119517-19-9
GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.
YN360628 Rosuvastatin D3 1133429-16-9
Rosuvastatin D3 (ZD 4522 D3) is a deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hE...
YN370396 MSDC-0602 1133819-87-0
MSDC-0602, a PPARγ-sparing thiazolidinedione (TZD), interacts with the mitochondrial pyruvate carrier (MPC) and inhibits its activity and has the potential for type 2 diabetes study with reducing risk of PPARγ-mediat...
YN270278 Pioglitazone D4 1134163-29-3
Pioglitazone D4 (U 72107 D4) is a deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selectivePPARγagonist with high affinity binding to the PPARγ lig and -binding domain withEC50of 0.93 and 0.99μ...
YN320247 SR59230A hydrochloride 1135278-41-9
SR59230A hydrochloride is a potent, selective, and blood-brain barrier penetratingβ3-adrenergic receptorantagonist with IC50s of 40, 408, and 648nM for β3, β1, and β2 receptors, respectively.
MK-0941 is a potent, orally active and allostericglucokinaseactivator, with EC50s of 240 and 65nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment...
YN330125 nor-NOHA acetate 1140844-63-8
nor-NOHA acetate (Nω-Hydroxy-nor-L-arginine acetate) is a specific and reversiblearginaseinhibitor, induces apoptosis in ARG2-expressing cells under hypoxia but not normoxia. Anti-leukemic activity, effective in endothelial dy...
YN481680 Emixustat 1141777-14-1
Emixustat, a novel visual cycle modulator, is an inhibitor of thevisual cycle isomerasewith an IC50 value of 4.4nMin vitro.
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