YN360292 Hyperforin dicyclohexylammoni... 238074-03-8

Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is atransient receptor canonical 6 (TRPC6)channels activator. Hyperforin dicyclohexylammonium salt modulates Ca2+levels by activating Ca2+-conducting non-selective canonica...

YN482815 Sibiricose A6 241125-75-7

Sibiricose A6 is an oligosaccharide ester isolated fromPolygalae Radixwith potent antioxidant activity.

YN360023 N-type calcium channel blocke... 241499-17-2

N-type calcium channel blocker-1 is an orally active analgesic agent which shows high affinity to functionally block N-type calcium channelswith an IC50 of 0.7μM in the IMR32 assay.

YN321337 Solifenacin 242478-37-1

Solifenacin is a novel muscarinic receptor antagonist with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.

YN321318 Solifenacin Succinate 242478-38-2

Solifenacin succinate is a urinary antispasmodic of the antimuscarinic class.

YN320713 JTC-801 244218-51-7

JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM, weakly inhibits receptors δ, κ, and μ.

YN321886 FSLLRY-NH2 245329-02-6

FSLLRY-NH2 is aprotease-activated receptor 2 (PAR2)inhibitor.

YN380276 Rubrofusarin triglucoside 245724-07-6

Rubrofusarin triglucoside is a glycoside compound isolated fromCassia obtusifolia Linnseeds. Rubrofusarin triglucoside inhibitshuman monoamine oxidase A (hMAO-A)with an IC50 of 85.5μM.

YN360010 Varenicline 249296-44-4

Varenicline is highly selective and blocks more potently to α4β2 receptors than to other common nicotinic receptors (>500-fold α3β4, >3,500-fold α7, >20,000-fold α1βγδ), or to non-nicotinic receptors and transporters (>2,000-fold)...

YN320389 SB-334867 249889-64-3

SB-334867 (SB 334867A) is an excellent,selective and blood–brain barrier permeableorexin-1 (OX1) receptorantagonist, shows selectivity overOX2(pKb=7.4), 100-fold over 5-HT2B, 5-HT2Cwith pKi values. of 5.4 and 5.3, resp...

YN300075 Dynamin inhibitory peptide 251634-21-6

Dynamin inhibitory peptide competitively blocks binding ofdynaminto amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide blocks the dopamine D3 effect on GABAA receptors.

YN300079 DynaMin inhibitory peptide, ... 251634-22-7

DynaMin inhibitory peptide, myristoylated is aDynaMininhibitor to interfere with the binding of amphiphysin with dynamin. DynaMin inhibitory peptide, myristoylated is a membrane-permeant form of the peptide that prevents endocytosis.

YN483494 Hydroxy-Epsilon-Sanshool 252193-26-3

Hydroxy-Epsilon-Sanshool is an alkylamide isolated fromZanthoxylum bungeanum. Hydroxy-Epsilon-Sanshool produces key tingling and numbing chemosensates, and its content is important in determinant the pungency intensity ofZanthox...

YN322010 T 82 252264-92-9

T 82 is a potent5-HT3antagonist and acetylcholinesterase (AChE)inhibitor, used for treatment of Alzheimer's Disease.

YN360102 TPA 023 252977-51-8

TPA 023 is aGABAA α2/α3subtype-selective agonist, with Kiof 0.19-0.41nM.

YN250099 Emricasan 254750-02-2

Emricasan is a potent irreversible pan-caspase inhibitor.

YN322098 SEW​2871 256414-75-2

SEW2871 is a highly selective, orally activeS1P1agonist with an EC50 of 13.8nM. SEW2871 activates ERK, Akt, and Rac signaling pathways and induces S1P1 internalization and recycling. SEW2871 reduces lymphocyte num...

YN480270 Secoisolariciresinol diglucos... 257930-74-8

Secoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuro...

YN480010 Enecadin 259525-01-4

Enecadin is a neuroprotective agent extracted from patent US 8623823 B2.

YN360276 TRPM8 antagonist 2 259674-19-6

TRPM8 antagonist 2 is a potent and selectiveTRPM8antagonist, with an IC50 of 0.2nM, used in the research of neuropathic pain syndromes.