YN380025 tCFA15 220757-88-0

tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulatesNotchsignaling.

YN330164 GW-406381 221148-46-5

GW406381, a highly selectivecyclooxygenase-2 (COX-2)inhibitor, attenuates spontaneous ectopic discharge in sural nerves of rats following chronic constriction injury.

YN320183 Y1 receptor antagonist 1 221697-09-2

Y1 receptor antagonist 1 (H 409-22 isomer) is aneuropeptide Y1 receptorantagonist.

YN440195 Rp-8-CPT-cAMPS sodium 221905-35-7

Rp-8-CPT-cAMPS sodium, a cAMP analog, is a potent and competitive antagonist of cAMP-induced activation of cAMP-dependentPKA I and II. Rp-8-CPT-cAMPS sodium preferentially selects site A of RI compares to...

YN320911 Adoprazine 222551-17-9

Adoprazine, a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties. Adoprazine is a full 5-HT1A receptor agonist and full D2/3 receptor antagonist possessing characteris...

YN450106 Ripasudil free base 223645-67-8

Ripasudil free base (K-115 free base) is a specific inhibitor ofROCK, with IC50s of 19 and 51nM forROCK2 and ROCK1, respectively.

YN320908 Mirabegron 223673-61-8

Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.

YN373998 Sch59498 224157-99-7

Sch59498 is a potent inhibitor ofphosphodiesterase 1c (Pde1c).

YN480154 GLN-1062 224169-27-1

Memogain is a pro-drug of galantamine, used for the treatment for Alzheimer’s disease.

YN480183 Miridesap 224624-80-0

Miridesap is a lig and forserum amyloid Pcomponent (SAP) and intends to inhibit and dissociateSAPbinding to amyloid fibrils and tangles.

YN360101 CP-409092 hydrochloride 225240-86-8

CP-409092 hydrochloride is a partial agonist ofGABAAreceptor, with anti-anxiety activity.

YN322080 Substance P Receptor Antag... 225526-17-0

Substance P Receptor Antagonist 1 has the potential function in central nervous system disorders, respiratory, inflammatory diseases and gastrointestinal disorders.

YN322077 AR-08 226081-74-9

AR-​08 is an agonist ofα2-adrenergic receptor, used for the treatment of attention deficit hyperactivety disorder (ADHD).

YN481437 Emapunil 226954-04-7

Emapunil(AC-5216) is a novel mitochondrial benzodiazepine receptor/translocator protein (MBR/TSPO) ligand. Emapunil(AC-5216) showes high affinity for MBRs prepared from rat whole brain with Ki of 0.297 nM and IC50...

YN360011 Varenicline Hydrochloride 230615-23-3

Varenicline (CP 526555) Hydrochloride is a potent and selective inhibitor of nicotine acetylcholine receptor (nAChR) with Ki of 0.12 nM and 0.14 nM for α6β2 nAChR and α4β2 nAChR, respectively.

YN321882 Neuropeptide SF(mouse,rat) 230960-31-3

Neuropeptide SF (mouse,rat) is a potentneuropeptide FF receptoragonist with Ki values are 48.4nM and 12.1nM for NPFF1 and NPFF2, respectively. Neuropeptide SF increases the amplitude of the sustained current of hetero...

YN360114 MK-0343 233275-76-8

MK0343 (MRK-409) is an orally bioavailableGABAAreceptor subtype-selective partial agonist. MK0343 is a non-sedating anxiolytic.

YN483907 Prolactin Releasing Peptide... 235433-36-0

Prolactin Releasing Peptide (12-31), human is a fragment of the prolactin releasing peptide (PrRP). Prolactin Releasing Peptide (1-31), human is a high affinityGPR10lig and that cause the release of the prolactin.

YN321898 [Arg14,Lys15]Nociceptin 236098-40-1

[Arg14,Lys15]Nociceptin is a highly potent and selectiveNOP receptor (ORL1; OP4)agonist, with an EC50 of 1nM. [Arg14,Lys15]Nociceptin displays high selectivity over opioid receptors, with IC50s of 0.32, 280, >10000 and...

YN360831 Eslicarbazepine acetate 236395-14-5

Eslicarbazepine acetate is an antiepileptic drug.