Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN1730024 Pridopidine 346688-38-8
Pridopidine, adopamine(DA) stabilizer, acts as a low affinitydopamine D2 receptor(D2R) antagonist. Pridopidine exerts high affinity towardssigma 1 receptor(S1R) withKibetween 70 and 80nM, which is ~100× higher than its affinit...
YN321564 Doxepin D3 Hydrochloride 347840-07-7
Doxepin D3 Hydrochloride is a deuterium labeled Doxepin Hydrochloride. Doxepin hydrochloride is an orally active tricyclic antidepressant. Doxepin hydrochloride is a potent and selectivehistamine receptor H1antagonist. Doxepin hy...
Optovin is a reversible photoactivatedTRPA1lig and that enables light-mediated neuronal excitation. Photo-excited Optovin directly alkylates cysteine residues in TRPA1 via rapid and reversible covalent bonding.
YN360506 HC-030031 349085-38-7
HC-030031 is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively.
Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM in RH7777 cell lines, respectively, shows no activity at LPA4, LPA5, LPA6.
YN480716 Seletracetam 357336-74-4
Seletracetam (Ucb 44212) is an analog of the antiepileptic agent Levetiracetam. Seletracetam is a small moleculeSV2Amodulator for the research of epilepsy .
YN321984 Urocortin III, mouse 357952-10-4
Urocortin III, mouse is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activatesCRF-R2. Urocortin III (Ucn3) is a known component of the behavioral stress response system...
YN321224 Roluperidone 359625-79-9
Roluperidone (CYR-101) is a novel cyclic amide derivative that has high equipotent affinities for5-HT2A and sigma-2receptors (Kiof 7.53nM and 8.19nM for 5-HT2A and sigma-2, respectively).
JDTic is a highly selective antagonist for the κ-opioid receptor; without affecting the μ- or δ-opioid receptors.
YN320560 Pitolisant 362665-56-3
Pitolisant is a potent and selective nonimidazole inverse agonist at the recombinant humanhistamine H3 receptor(Ki=0.16nM).
YN320561 Pitolisant oxalate 362665-57-4
Pitolisant oxalate is a potent and selective nonimidazole inverse agonist at the recombinant humanhistamine H3 receptor(Ki=0.16nM).
YN321377 Lurasidone 367514-87-2
Lurasidone is a second-generation antipsychotic agent that exhibits full antagonism at dopamine D2 and serotonin 5-HT2A receptors with binding affinities Ki = 1 nM and Ki = 0.5 nM, respectively. It also has high affinity for serot...
YN321376 Lurasidone Hydrochloride 367514-88-3
Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is an antagonist of bothdopamine D2 and 5-HT7with IC50s of 1.68 and 0.495nM, respectively. Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is also a partial agon...
YN370335 Arimoclomol citrate 368860-21-3
Arimoclomol citrate (BRX-220 citrate) is a co-inducer of heat shock proteins (HSP). Arimoclomol citrate protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded as...
YN484052 BigLEN(rat) 369377-66-2
BigLEN(rat), one of the most abundant peptides in brain, is a potentGPR171agonist, with an EC50 of 1.6nM.
YN484274 Neuromuscular Disorder-Targ... 374538-23-5
Neuromuscular Disorder-Targeting Compound 1 is used in the research of neuromuscular disorders such as symptoms of fibromyalgia syndrome and chronic fatigue syndrome.
ASP2535 is a potent, orally bioavailable, selective, brain permeable and centrally-activeglycine transporter-1 (GlyT1)inhibitor. ASP2535 can improve cognitive impairment in animal models of schizophrenia and Alzheimer's disease...
YN360236 Mibampator 375345-95-2
Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors.
YN360013 Varenicline Tartrate 375815-87-5
Varenicline Tartrate is a nicotinic AChR partial agonist, used to treat nicotine addiction.
LY450108 is a potentAMPAreceptor potentiator. LY450108 has the potential for depression and Parkinson's disease research.
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