YN1730029 Preladenant 377727-87-2

Preladenant (Privadenant, SCH 420814, MK-3814) is a potent, competitive and selective antagonist of the human adenosine A_{2A receptor with Ki of 1.1 nM.}

YN360350 CMPDA 380607-77-2

CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ± 4.2nM/63.4 ± 5.6nM for GluA2i/GluA2o receptor.

YN321897 [(pF)Phe4]Nociceptin(1-13)N... 380620-88-2

[(pF)Phe4]Nociceptin(1-13)NH2 is a highly potent and selectiveNOP receptor (OP4)agonist, with a pKi of 10.68 and apEC50of 9.31. [(pF)Phe4]Nociceptin(1-13)NH2 displays high selectivity over δ, κ, and μ opioid recep...

YN483160 Bacopaside I 382148-47-2

Bacopaside I, a saponin isolated fromBacopa monniera, exbibits antioxidant properties and free radical scavenging capacity and exerts antidepressant-like effect.

YN483822 Neuropeptide W-23(human) 383415-79-0

Neuropeptide W-23(human), the active form of Neuropeptide W, is an endogenous lig and for NPBW1 and NPBW2.

YN380181 Desvenlafaxine succinate hydr... 386750-22-7

Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively.

YN484269 2: PN: US20040072744 SEQ... 389572-87-6

2: PN: US20040072744 SEQID: 2 claimed protein is a synthetic peptide, used for the research of Down's syndrome and schizophrenia.

YN320558 JNJ-5207852 398473-34-2

JNJ-5207852 is a selective and potenthistamine H3receptor (H3R) antagonist, withpKisof 8.9, 9.24 for rat and human H3R, respectively.

YN484276 Oiligodendrocyte differentiat... 400760-25-0

Oiligodendrocyte differentiation promoter 1 belongs to the oiligodendrocyte differentiation promoter.

YN300037 Firategrast 402567-16-2

Firategrast (SB 683699) is an orally active and specificα4β1/α4β7 integrinantagonist. Firategrast reduces trafficking of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity .

YN320231 SB-399885 hydrochloride 402713-81-9

SB-399885 hydrochloride is a5-HT6receptorantagonist.

YN482851 6-Methoxykaempferol 3-O-Rut... 403861-33-6

6-Methoxykaempferol 3-O-Rutinoside is a natural product isolated from the herbs ofPilocarpus pennatifolius.

YN360187 NFPS 405225-21-0

NFPS is a selective, non-competitiveglycine transporter-1 (GlyT1)inhibitor with IC50s of 2.8nM and 9.8nM for hGlyT1 and rGlyT1, respectively. NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of tra...

YN480649 BCATc Inhibitor 2 406191-34-2

BCATc Inhibitor 2 is a selective branched-chain aminotransferase (BCAT) inhibitor for research of neurodegenerative diseases. The IC50s of 0.2μM, 0.8μM and 3.0μM for rat cytosolic isoenzyme rBCATc, human cytosolic is...

YN321906 Ac-RYYRWK-NH2 TFA 408305-09-9

Ac-RYYRWK-NH2 is a potent and selective partial agonist for thenociceptin receptor (NOP), [3H]Ac-RYYRWK-NH2 binds to rat cortical membranes ORL1 with aKdof 0.071nM, but has no affinity for µ-, κ- or δ-opioid ...

YN320044 JNJ16259685 409345-29-5

JNJ16259685 is a selective antagonist ofmGlu1 receptor, and inhibits the synaptic activation of mGlu1 in a concentration-dependent manner with IC50 of 19nM.

YN320727 VU0152100 409351-28-6

VU0152100 is a potent and selective allosteric potentiator of M4 mAChR with an EC50 of 380 ± 93nM.

YN322095 CCG 203769 410074-60-1

CCG 203769 is a selective G protein signaling (RGS4) inhibitor, which blocks the RGS4-Gαoprotein-protein interaction in vitro with an IC50 of 17nM.

YN380131 Amitifadine hydrochloride 410074-74-7

Amitifadine hydrochloride is a serotonin-norepinephrine-dopamine reuptake inhibitor(SNDRI), with IC50s of 12, 23, 96nM for serotonin, norepinephrine and dopamine in HEK 293 cells , respectively.

YN321506 Tiotropium bromide hydrate 411207-31-3

Tiotropium Bromide hydrate is an anticholinergic and bronchodilator and a muscarinic receptor antagonist. Tiotropium bromide (Ba 679 BR) is a novel potent and long-lasting muscarinic antagonist that has been developed for the tr...