YN360427 TCN 201 852918-02-6

TCN 201 is a potent, selective and non-competitive antagonist ofGluN1/GluN2AnMDA receptor, with apIC50 of 6.8. TCN 201 is selective for GluN1/GluN2AnMDA receptor over GluN1/GluN2BnMDA receptor (pIC50<4.3)...

YN481563 Trofinetide 853400-76-7

Trofinetide (NNZ-2566), a synthetic analogue of the endogenous N-terminus tripeptide, Glycine-Proline-Glutamate (GPE), has been shown to be neuroprotective in animal models of brain injury.

YN360805 Ropivacaine mesylate 854056-07-8

Ropivacaine Mesilate is the mesylate form of ropivacaine, which is a member of the amino amide class of local anesthetics.

YN450054 HLY78 854847-61-3

HLY78 is an activator of theWnt/β-cateninsignaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction.

YN330216 OBA-09 856095-68-6

OBA-09, a simple ester of pyruvate and salicylic acid, is potent multi-modal neuroprotectant. OBA-09 has anti-oxidative and anti-inflammatory effects.

YN483368 Polygalaxanthone XI 857859-82-6

Polygalaxanthone XI, a xanthone glycoside isolated from the cortexes ofPolygala tenuifolia, can be used in the study of expectorant, sedative, and tranquilizing agent.

YN481674 Latanoprostene bunod 860005-21-6

Latanoprostene bunod (LBN), a nitric oxide (NO)-donating prostagl and in F2a analog, is a topical ophthalmic therapeutic for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (...

YN360438 A2764 dihydrochloride 861038-72-4

A2764 dihydrochloride is a selective inhibitor of TRESK (TWIK-related spinal cord K+ channel, K2P18.1) with IC50 of 11.8 μM for the activated mTRESK channel. A2764 dihydrochloride has the potential for probing ...

YN360709 A-740003 861393-28-4

A-740003 is a potent, selective and competitiveP2X7 receptorantagonist with IC50 values are 18 and 40nM for rat and human P2X7 receptors, respectively.

YN322020 MK-0249 862309-06-6

MK-0249 is a potenthistamine H3 receptorantagonist, with Kiof 1.7nM for human H3.

YN483698 D-Heptamannuronic acid 862694-97-1

D-Heptamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Heptamannuronic acid can be used for the research of pain and vascular dementia.

YN483699 D-Octamannuronic acid 862694-98-2

D-Octamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Octamannuronic acid can be used for the research of pain and vascular dementia.

YN483700 D-Nonamannuronic acid 862694-99-3

D-Nonamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Nonamannuronic acid can be used for the research of pain and vascular dementia.

YN320269 S 38093 862896-30-8

S 38093 is a histamine H3 antagonist/inverse agonist with a moderate affinity for rat, mouse and human H3 receptors (Ki = 8.8, 1.44 and 1.2 μM, respectively) and no affinity for other histaminergic receptors.

YN320999 Cebranopadol 863513-91-1

Cebranopadol is an analgesicNOP and opioid receptoragonist with Kis/EC50s of 0.9nM/13nM, 0.7nM/1.2nM, 2.6nM/17nM, 18nM/110nM for human NOP, MOP, KOP  and  delta-opioid peptide (DOP) receptor, respecti...

YN1730085 GSK598809 863680-45-9

GSK598809 is a potent and selective dopamine D3 Receptor(DRD3)antagonist, with a pKi of 8.9.

YN310373 ZIP 863987-12-6

ZIP is a selective peptide inhibitor ofPKMζ. ZIP injections can block the impairment in morphine conditioned place preference induced.

YN330205 Succinyl phosphonate trisodiu... 864167-45-3

Succinyl phosphonate trisodium salt is an α-ketoglutarate dehydrogenase (KGDHC) inhibitor, effective inhibits (KGDHC) in muscle, bacterial, brain, and cultured human fibroblasts . Succinyl phosphonate trisodium salt is an 2-...

YN290287 MK-28 864388-65-8

MK-28 is a potent and selectivePERKactivator. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice.

YN360455 5-AMAM-2-CP 864628-19-3

5-AMAM-2-CP is a major metabolite of Acetamiprid. Acetamiprid is a neonicotinoid insecticide used worldwide and is a nAChR agonist.