Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN320006 Taranabant racemate 701977-00-6
Taranabant racemate (MK-0364 racemate) is an antagonist and /or inverse agonist of the Cannabinoid-1(CB1) receptorextracted from patent WO 2004048317 A1.
SUN11602 is a small synthetic compound that mimics the neuroprotective activities of bFGF and activates key molecules in the FGF receptor-1-mitogen-activated protein kinase/extracellular signal-regulated kinase-1/2 kinase (FGFR...
YN361042 α-Conotoxin PnIA 705300-84-1
α-Conotoxin PnIA, a potent and selective antagonist of the mammalianα7 nAChR, has the potential for the research of neurological conditions such as neuropathic pain and Alzheimer’s disease.
YN320888 Pimavanserin 706779-91-1
Pimavanserin is a selective inverse agonist of the5-HT2Areceptor withpIC50 and pKdof 8.73 and 9.3, respectively.
YN320889 Pimavanserin tartrate 706782-28-7
Pimavanserin is a potent and selective serotonin 5-HT2A inverse agonist with pIC50 of 8.73, used to treat psychosis associated with Parkinson’s disease.
SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.
YN320451 HAMI 3379 712313-35-4
HAMI 3379 is a potent and selectiveCysteinyl leukotriene (CysLT2) receptorantagonist. HAMI 3379 has a protective effect on acute and subacute ischemic brain injury, and attenuates microglia-related inflammation.
APETx2, a sea anemone peptide fromAnthopleura elegantissima, is a selective and reversibleASIC3inhibitor, with an IC50 of 63nM. APETx2 directly inhibits the ASIC3 channel by acting at its external side. APETx2 coul...
YN360812 Tetrabenazine Racemate 718635-93-9
Tetrabenazine Racemate (Ro 1-9569 Racemate) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2). (1) The reference for administration is 0.25-0.75 mg/kg IP (2) Injections of tetrabenazine int...
YN320817 GSK189254A 720690-73-3
GSK189254A (GSK189254) is a novel, potent and selective histamineH3receptor antagonist with pKi values. of 9.59-9.90 and 8.51-9.17 for human and rat H3, respectively.
YN370320 GSK356278 720704-34-7
GSK356278 is a potent, selective, orally bioavailable and brain-penetrant inhibitor ofphosphodiesterase 4 (PDE4), with pIC50s of 8.6, 8.8, and 8.7 for human PDE4A, PDE4B, and PDE4D, respectively. GSK356278 has a...
YN420142 BpV(HOpic) 722494-26-0
bpV (HOpic) is a potent inhibitor of PTEN with an IC50 of 14 nM. The IC50s for PTP-β and PTP-1B are about 350- and 1800-fold higher than the IC50 for PTEN, respectively.
YN1730041 A-381393 726174-00-1
A-381393 is a potent, selective, brain penetratedopamine D4receptorantagonist, with Kis of 1.5, 1.9 and 1.6nM for human dopamine D4.4, D4.2, and D4.7receptor, respectively, >2700-fold selectivity over D1, D2, D3 and D5dopami...
YN360377 SCH 50911 733717-87-8
SCH 50911, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid BGABA(B)receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1μM. SCH 50911 antagoni...
Ivachtin (Caspase-3 Inhibitor VII; compound 7a) is a nonpeptide, noncompetitive and reversiblcaspase-3inhibitor with an IC50 of 23nM. Ivachtin has modest selectivity for the remaining caspases.
UBP 302 is a potent and selectiveGLUK5-subunit containing kainate receptorantagonist (apparentKd=402nM), and displays very little affinity on GluK2 (GluR6) kainate receptors. Anxiolytic effects .
YN370343 CS-722 Free base 749179-13-3
CS-722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex. CS-722 Free base inhibits spontaneous inhibitory postsynaptic currents and excita...
YN380099 Itanapraced 749269-83-8
CHF5074 is a gamma-secretase modulator that reduces Aβ42 and Aβ40 secretion. The IC50s of CHF5074 for inhibition of COX-1 and COX-2 is above 100 μmol/L.
EHT 1864 2HCl is a potent Rac family GTPase inhibitor with Kd of 40 nM, 50 nM, 60 nM and 250 nM for Rac1, Rac1b, Rac2 and Rac3, respectively.
YN483026 N-Methylnuciferine 754919-24-9
N-Methylnuciferine, an alkaloid fromLotus Plumule, ameliorate lipopolysaccharide-induced depression-like behavior.
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