YN360043 U93631 152273-12-6

U93631 is a GABAA receptor lig and of novel chemical structure with IC50 of 100nM, and has been shown to induce a rapid, time-dependent decay of GABA-induced whole-cell Cl-currents in recombinant GABAA receptors.

YN380285 Amyloid β-Protein 10-20 152286-31-2

Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.

YN320722 7-Desmethyl-agomelatine 152302-45-9

7-Desmethyl-agomelatine is a metabolite of Agomelatine. Agomelatineis a potent agonist at melatonin receptors (MT1 and MT2), and also is an antagonist of 5-HT2C.

YN320181 Alniditan 152317-89-0

Alniditan is a potent5-HT1B/1Dreceptorsagonist, with IC50 of 1.7 and 1.3nM in HEK 293 cells,and pKivalue of 8.96 and 9.40 for 5-HT1B/1Dreceptors, respectively.

YN320635 Nalfurafine 152657-84-6

Nalfurafine (TRK-820) is a potent selective and orally active G protein-biasedkappa opioid receptor (KOR)-agonist with high translational potential. Nalfurafine (TRK-820) enhances the therapeutic potential of MOR-targeting...

YN320636 Nalfurafine hydrochloride 152658-17-8

Nalfurafine hydrochloride (TRK-820 hydrochloride) is a potent selective  and  orally active G protein-biasedkappa opioid receptor (KOR)-agonist with high translational potential. Nalfurafine hydrochloride (TRK-820 h...

YN1730120 U91356 152886-85-6

U91356 is adopamine receptoragonist.

YN1730083 AB-MECA 152918-26-8

AB-MECA is a high affinity A3 adenosine receptor agonist, has high affinity for recombinant A1 and A3 receptors.

YN360201 Lanicemine 153322-05-5

Lanicemine (AZD6765) is a low-trappingNMDA channel blockerwith a binding (Ki) of 0.56-2.1 μM.

YN280154 Ginkgolide K 153355-70-5

Ginkgolide K, isolated fromGinkgo biloba, induces protective autophagy through the AMPK/mTOR/ULK1 signaling pathway. Ginkgolide K possesses neuroprotective activity.

YN321310 Cevimeline hydrochloride hemi... 153504-70-2

Cevimeline (AF 102B, SNI 2011, SNK 508) is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3.

YN321912 [D-Trp34]-Neuropeptide Y 153549-84-9

[D-Trp34]-Neuropeptide Y is a potent and selectiveneuropeptide Y (NPY) Y5receptoragonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6receptors. [D-Trp34]-Neuropepti...

YN361076 S16961 153874-14-7

S16961 is anicotinic receptoragonist.

YN360097 RPR104632 154106-92-0

RPR104632 is a specific antagonist of NMDA receptor, with potent neuroprotective properties.

YN320369 PD 144418 154130-99-1

PD 144418 is a highly affinity, potent and selectivesigma 1 (σ1) receptorlig and (Kivalues of 0.08nM and 1377nM forσ1 and σ2 respectively). PD 144418 devoids of any significant affinity for other receptors, ion channels and...

YN360515 YM90K 154164-30-4

YM90K is a potent and selectiveAMPA receptorantagonist with a Ki of 84nM. YM90K is less potent in inhibiting kainate (Kiof 2.2μM) and nMDA (Kiof 37μM) receptors. YM90K has neuroprotective actions.

YN360235 CX516 154235-83-3

Ampalex (CX-516, Ampakine CX 516, BDP-12, SPD 420) is a positive allosteric modulator of AMPA receptor. Ampalex exhibits potential treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MC...

YN321478 Almotriptan 154323-57-6

Almotriptan is a 5-HT1B/1D-receptor agonist used to treat migraine. Almotriptan is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults. Almotriptan showed low...

YN1730028 Istradefylline 155270-99-8

Istradefylline is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3.

YN1730118 KF21213 155271-17-3

KF21213 is a highly selective lig and for mapping CNS adenosineA2Areceptors. KF21213 shows a high affinity for the adenosineA2Areceptors (Ki=3.0nM).