YN321009 Piboserod hydrochloride 178273-87-5

Piboserod (SB 207266) Hcl is a selective 5-HT(4) receptor antagonist.

YN320824 Prucalopride 179474-81-8

Prucalopride is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.

YN320628 Prucalopride succinate 179474-85-2

Prucalopride is a selective, high affinity 5-HT4 receptor agonist. The Ki values of prucalopride for human 5-HT(4a) and 5-HT(4b) receptor are 2.5 nM and 8 nM, respectively.

YN321258 Eptapirone 179756-58-2

Eptapirone (F11440) is a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential.

YN320102 SB-224289 hydrochloride 180084-26-8

SB-224289 hydrochloride is a selective5-HT1B receptorantagonist, with anxiolytic effect.

YN321477 Almotriptan malate 181183-52-8

Almotriptan Malate is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.

YN320244 SB228357 181629-93-6

SB228357 is a selective, potent and orall active5-HT2C/2Breceptorantagonist with pKi values. of 6.9, 8.0 and 9.0 for5-HT2A,5-HT2B and 5-HT2C, respectively. SB228357 has antidepressant/anxiolytic effects.

YN320732 SB 242084 181632-25-7

SB 242084 is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.

YN320233 LY334370 182563-08-2

LY334370 is a selective5-HT1Freceptor agonist with a Ki of 1.6nM.

YN320163 Abaperidone 183849-43-6

Abaperidone is a potent antagonist of 5-HT2A receptor and dopamine D2receptor with IC50s of 6.2 and 17nM.

YN322089 5-HT3-In-1 186348-68-5

5-HT3-In-1 is extracted from patent EP0748807A1, compound example 8. It shows5-HT3inhibition activity.

YN320805 LY 344864 racemate 186543-64-6

LY 344864 racemate is a5-HT1Freceptoragonist extracted from patent US 5708187 A.

YN320802 LY 344864 186544-26-3

LY 344864 is a selective receptor agonist with an affinity of 6nM (Ki) at the recently cloned 5-HT1F receptor.

YN320803 LY 344864 S-enantiomer 186544-27-4

LY 344864 S-enantiomer is the S-enantiomer of LY344864. LY344864 is a 5-HT1F receptor agonist.

YN320870 ML 10302 hydrochloride 186826-17-5

ML 10302 hydrochloride is a potent and selective5-HT4receptoragonist, with an EC50 of 4nM。ML 10302 hydrochloride displays more than 680-fold selectivity over5-HT3receptor in binding assay.

YN320240 PNU-142633 187665-65-2

PNU-142633 is a high affinity, selective and orally active5-HT1Dreceptoragonist with Kis of 6nM and > 18 000nM for human5-HT1Dreceptor and human 5-HT1Breceptor, respectively. PNU-142633 has anti-migraine efficacy.

YN320825 Tegaserod maleate 189188-57-6

Tegaserod Maleate is a hydrogen maleate salt form of tegaserod, which is a 5-HT4 receptor partial agonist and binds with high affinity to 5-HT4 receptors. It has limited affinity for 5-HT1 receptors and no appreciable affinity for ...

YN322074 5-HT2 antagonist 1 191592-09-3

5-HT2 antagonist 1 is a potent antagonist of5-HT2 receptor, with weakα1 adrenoceptorblocking activity.

YN320748 LY310762 192927-92-7

LY310762 is a 5-HT1D receptor antagonist with Ki of 249nM, having a weaker affinity for 5-HT1B receptor. IC50 value: 249nM (Ki)

YN320702 BRL-15572 dihydrochloride 193611-72-2

BRL-15572 is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor.