YN321236 Pumosetrag Hydrochloride 194093-42-0

Pumosetrag Hydrochloride (MKC-733; DDP-733) is an orally available5-HT3partial agonist developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.

YN322096 SB 258719 195199-95-2

SB 258719 is a selective5-HT7receptorantagonist with a pKi of 7.5.

YN321330 Paliperidone palmitate 199739-10-1

Paliperidone palmitate (9-Hydroxyrisperidone palmitate), an atypical long-acting antipsychotic agent, is an ester prodrug of Paliperidone. Paliperidone is adopamineantagonist and 5-HT2Aantagonist of the atypical antipsychotic class....

YN320982 RS-127445 hydrochloride 199864-86-3

RS-127445 hydrochloride is a selective, high affinity, orally bioavailable5-HT2Breceptorantagonist with a pKi of 9.5. RS-127445 hydrochloride shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ...

YN320983 RS-127445 199864-87-4

RS-127445 is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.

YN320236 SB 243213 200940-22-3

SB 243213 is an orally active, selective and high-affinity5-HT2Creceptorantagonist with a pKi of 9.37 and apKbof 9.8 for human 5-HT2Creceptor. SB 243213 shows greater than a 100-fold selectivity over a wide range of neurotra...

YN320234 SB 243213 hydrochloride 200940-23-4

SB 243213 hydrochloride is an orally active, selective and high-affinity5-HT2Creceptorantagonist with a pKi of 9.37 and apKbof 9.8 for human 5-HT2Creceptor. SB 243213 hydrochloride shows greater than a 100-fold selectivity o...

YN320967 SB-269970 201038-74-6

SB269970 is a5-HT7 receptorantagonist withpKiof 8.3, exhibits >50-fold selectivity against other receptors.

YN320851 Ro 04-6790 202466-68-0

Ro 04-6790 is a potent, competitive and selective5-HT6receptor antagonist with pKi values. of 7.26, 7.35 for rat and human 5-HT6 receptors, respectively. Ro 04-6790 has no affinity at other receptors.

YN322057 5-HT2A antagonist 1 204643-75-4

5-HT2A antagonist 1 is a5-HT2Aantagonist extracted from patent US5728835A and JP 1007727. 5-HT2A antagonist 1 may be useful in treatment of gastrointestinal disorders circulatory disorders.

YN320169 NRA-0160 204718-47-8

NRA-0160 is a selectivedopamine D4 receptorantagonist, with aKivalue of 0.48nM and with negligible affinity fordopamine D2 receptor(Ki: >10000nM),D3 receptor(Ki: 39nM), rat5-HT2A receptor(Ki: 180nM) and ratα1 adrenocep...

YN320278 Nemifitide diTFA 204992-09-6

Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. Nemifitide diTFA is a peptide analog of melanocyte-inhibiting factor (MIF). Nemifitide diTFA can ...

YN320912 Befiradol 208110-64-9

Befiradol (NLX-112) is a selective5-HT1Areceptor agonist.

YN320852 SB 271046 Hydrochloride 209481-24-3

SB 271046 hydrochloride is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9, exhibits 200-fold greater selectivity over other 5-HT receptor subtypes.

YN321262 Org-12962 hydrochloride 210821-63-9

Org 12962 hydrochloride is a potent, selective and efficacious 5-HT2Creceptor agonist and exhibitspEC50values of 7.01, 6.38 and 6.28 for 5-HT2C, 5-HT2A and 5-HT2A, respectively. Org 12962 hydrochloride is effective in...

YN321900 CART(62-76)(human,rat) 210978-19-1

CART(62-76)(human,rat) is a neuropeptide (62-76 residues of the CART peptide) with neurotransmitter-like effects. CART(62-76)(human,rat) can modulate the activity of striatal noradrenergic and corticostriatal and hypothalami...

YN320363 SB-277011 hydrochloride 215804-67-4

SB-277011 hydrochloride (SB-277011A hydrochloride) is a potent, selective, orally bioavailable and brain penetratedopamine D3receptor (D3R)antagonist with Ki values of 10.7 nM and  11.2nM at rodent and human D3R, resp...

YN320172 Sulamserod 219757-90-1

Sulamserod is a5-HT4 receptorantagonist, with antiarrhythmic activities.

YN322078 Revexepride 219984-49-3

Revexepride is a highly selective5-HT4 receptoragonist, and a potential inducer ofCYP3A4 enzyme, used for the treatment of gastroesophageal reflux disease.

YN320313 AR-A 2 220051-79-6

AR-A 2 is a selective5-HT1Breceptorantagonist, with high affinity to guinea pig cortex5HT1B/1D and recombinant guinea pig5-HT1Breceptors(Ki=0.24 and 0.47nM) and with 10-fold lower affinity to guinea pig5-HT1Dreceptor(...