YN372660 Otamixaban 193153-04-7

Otamixaban(FXV673) is a potent (Ki = 0.5nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. Otamixaban is a potent (Ki = 0.5nM), selective,...

YN483245 Terrestrosin K 193605-07-1

Terrestrosin K, a steroidal saponin fromTribulus terrestrisL., has potential to treat cardiovascular and cerebrovascular diseases.

YN310312 TAS-301 193620-69-8

TAS-301 is an inhibitor of smooth muscle cell migration and proliferation and inhibits intimal thickening after balloon injury to rat carotid arteries.

YN320532 A-192621 195529-54-5

A-192621 is a potent, nonpeptide, orally active and selectiveendothelin B (ETB) receptorantagonist with an IC50 of 4.5nM and a Ki of 8.8nM. The selectivity of A-192621 is 636-fold higher than ETA(IC50 of 4280nM and K...

YN320975 Atrasentan hydrochloride 195733-43-8

Atrasentan hydrochloride (ABT-627 hydrochloride) is a selectiveendothelin A receptorantagonist with an IC50 of 0.0551nM for ETA.

YN484055 PAMP-12(human, porcine) 196305-05-2

PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, is processed from the adrenomedullin precursor, is a potent hypotensive peptide and participates in cardiovascular control.

YN300074 Gap 26 197250-15-0

Gap 26, a connexin mimetic peptide that composeds of residue no. 63-75 of the extracellular loop 1 of connexin 43 (Cx43), is a gap junction inhibitor. Gap 26 blocks photoliberating inositol-1,4,5-trisphosphate triggers ATP rel...

YN321813 TFLLR-NH2 197794-83-5

TFLLR-NH2 is a selectivePAR1agonist with an EC50 of 1.9μM.

YN300068 Gap 27 198284-64-9

Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment.

YN380148 Safinamide mesylate 202825-46-5

Safinamide Mesylate is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. Phase 3.

YN481401 Lomitapide mesylate 202914-84-9

Lomitapide Mesylate is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.

YN360560 Istaroxime 203737-93-3

Istaroxime (PST2744) is a potent inhibitor ofNa+,K+-ATPasewith IC50 of 0.11μM.

YN1730086 Tecadenoson 204512-90-3

Tecadenoson (CVT-510) is a selectiveA1 adenosine receptoragonist.

YN322057 5-HT2A antagonist 1 204643-75-4

5-HT2A antagonist 1 is a5-HT2Aantagonist extracted from patent US5728835A and JP 1007727. 5-HT2A antagonist 1 may be useful in treatment of gastrointestinal disorders circulatory disorders.

YN483715 Korepimedoside C 205445-00-7

Korepimedoside C (Epimedin I), a flavonol glycoside, is isolated from the aerial parts ofEpimedium koreanumNakai.Epimedium koreanumNakai is a famous Chinese herbal medicine for the research of impotence, osteoporosis, immune suppre...

YN320051 Rilmenidine hemifumarate 207572-68-7

Rilmenidine hemifumarate, an innovative antihypertensive agent, is an orally active, selectiveI1 imidazoline receptoragonist. Rilmenidine hemifumarate is analpha 2-adrenoceptoragonist. Rilmenidine hemifumarate induces autophagy. Rilmen...

YN320427 Sitaxsentan sodium 210421-74-2

Sitaxsentan sodium (IPI 1040 sodium; TBC11251 sodium) is an orally active, highly selective antagonist ofendothelin A receptors.

YN482272 Cy5.5 210892-23-2

Cy5.5 (Sulfo-Cyanine5.5) is a near-infrared fluorescent dye (Ex=673nM, Em=707nM) used to label biological molecules, such as peptides, proteins, and oligonucleotides.

YN481218 Anhydrosimvastatin 210980-68-0

Anhydrosimvastatin (Impurity C) is an impurity of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase.

YN372245 Dalcetrapib 211513-37-0

Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM that increases the plasma HDL cholesterol. Phase 3.