YN483742 Palmitoyl Tetrapeptide-3 221227-05-0

Palmitoyl Tetrapeptide-3 is a synthetic peptide, corrspending to 341-344 amino acid sequence of IgG human H-chain, with phagocytosis stimulating activity.

YN483616 Anemarrhenasaponin Ia 221317-02-8

Anemarrhenasaponin Ia, isolated fromAnemarrhenaerhizome, inhibits N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide generation. Anemarrhenasaponin Ia is an useful anti-inflammation reagent.

YN320388 RO1138452 221529-58-4

RO1138452 is a potent and selectiveIP(prostacyclin)receptorantagonist. RO1138452 displays high affinity for IP receptors. In human platelets,pKiis 9.3±0.1; in a recombinant IP receptor system,pKiis 8.7±0.06.

YN440195 Rp-8-CPT-cAMPS sodium 221905-35-7

Rp-8-CPT-cAMPS sodium, a cAMP analog, is a potent and competitive antagonist of cAMP-induced activation of cAMP-dependentPKA I and II. Rp-8-CPT-cAMPS sodium preferentially selects site A of RI compares to...

YN330664 Lyn peptide inhibitor 222018-18-0

Lyn peptide inhibitor is a potent and cell-permeable inhibitor ofLyn-coupled IL-5 receptorsignaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the binding ofLyn tyrosine ...

YN360060 YM-58483 223499-30-7

YM-58483/BTP2 is a blocker of store-operated Ca2+ entry (SOCE), which regulates the activation of non-excitable cells such as lymphocytes.

YN250128 Rupintrivir 223537-30-2

Rupintrivirvr (AG7088), an antiviral drug, is a potent, selective and irreversible inhibitor ofhuman rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and...

YN373995 PDE IV-IN-1 225100-12-9

PDE IV-IN-1 is an inhibitor ofphosphodiesterase IV, used for the research of asthma, COPD or other inflammatory diseases.

YN322080 Substance P Receptor Antag... 225526-17-0

Substance P Receptor Antagonist 1 has the potential function in central nervous system disorders, respiratory, inflammatory diseases and gastrointestinal disorders.

YN320357 CCR2 antagonist 4 226226-39-7

CCR2 antagonist 4 (Teijin compound 1) is a potent and specificCCR2antagonist, with IC50s of 180nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24nM.

YN360457 Lansoprazole sodium 226904-00-3

Lansoprazole sodium (AG 1749 sodium) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole sodium (AG 1749 sodium) is a potent brain penetrantneutral sphingomyelinase (N-SMase)inhibi...

YN480139 Sotirimod 227318-75-4

Sotirimod is an immunostimulant, and can potentially treat for actinic keratosis.

YN300038 MK-0429 227963-15-7

MK-0429 (L-000845704) is an orally active, potent, selective and nonpeptidepan-integrinantagonist with IC50 values of 1.6nM, 2.8nM, 0.1nM, 0.7nM, 0.5nM and 12.2nM for αvβ1, αvβ3, αvβ5, αvβ6, αvβ8 and α5β1, respe...

YN320731 TAK-779 229005-80-5

TAK-779 is a potent and selective nonpeptide antagonist ofCCR5 and CXCR3, with a Ki of 1.1nM for CCR5, and effectively and selectively inhibitsR5 HIV-1, withEC50 and EC90of 1.2nM and 5.7nM, respectively, in ...

YN340161 Golotimod 229305-39-9

Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golo...

YN371163 α-D-Glucose-1-phosphate dis... 230954-92-4

α-D-Glucose-1-phosphate disodium hydrate is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium hydrate can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiot...

YN370360 UK 356618 230961-08-7

UK 356618 (Compound 4j) is a potent and selective inhibitor ofmatrix metalloprotease-3 (MMP-3)with an IC50 of 5.9nM. UK 356618 is less potent against MMP-1, MMP-2, MMP-9, MMP-13 and MMP-14 compared withMMP-3...

YN370378 UK-370106 230961-21-4

UK-370106 is a potent and highly selectiveMMP-3(IC50 of 23nM) and MMP-12(IC50 of 42nM) inhibitor with >1200-fold higher potency than MMP-1, MMP-2, MMP-9, and MMP-14, and about 100-fold than MMP-13 and M...

YN300040 TR-14035 232271-19-1

TR-14035 (SB 683698, MDK-1191) is a a dual alpha4beta (α4β) integrin antagonist with IC50 of 7 nM and 87 nM for alpha4beta7 (α4β7) and alpha4beta1 (α4β1), respectively.

YN484157 LCMV GP (61-80) 232598-19-5

LCMV GP (61-80) is a peptide fragment derived from lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP), and corresponds to amino acids 61-80. LCMV GP (61-80) is a specific epitope which can induce CD4+T-cell r...