Chemical structure
Cat.No.
Product Name
CAS no.
Target
CPYPP is aDOCK2-Rac1 interactioninhibitor. CPYPP binds toDOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity ofDOCK2DHR-2for Rac1 in a dose-dependent manner with an IC50 ...
IQ 3 is a specific c-Jun N-terminal kinase (JNK) inhibitor with Kd of 66 nM, 240 nM and 290 nM for JNK3, JNK1 and JNK2, respectively. IQ 3 inhibits LPS-induced NF-κB/AP1 transcriptional activity ...
PROTO-1 shows significant protection of hair cells, with HC50(concentration that would produce 50% hair cell survival) of 1μM-10μM (1μM≤HC50≤10μM).
MMG-11 is a potent and selective humanTLR2antagonist with low cytotoxicity. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with IC50s of 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-i...
YN320737 CID-1067700 314042-01-8
CID-1067700 (ML282) is a panGTPaseinhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a Ki of 13nM.
STING inhibitor C-176 is a potent, small-molecule inhibitor of STING , a central signaling component of the intracellular DNA sensing pathway.
YN483743 Thymus peptide C 316791-23-8
Thymus peptide C is a hormonal drug derived from the thymus gl and s of young calves, which works as a substitute for the physiological functions of the thymus.
GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ.
TCS 2314 (compound 3) is orally active and selectivevery late antigen-4 (VLA-4, α4β1, CD49d/CD29)antagonist with an IC50 of 4.4nM.
YN320822 Aclidinium Bromide 320345-99-1
Aclidinium Bromide inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.
YN321875 [D-Trp8]-γ-MSH 321351-81-9
[D-Trp8]-γ-MSH is a potent and selective agonist ofmelanocortin 3 (MC3) receptor, with IC50s of 6.7nM, 600nM and 340nM forhMC3,hMC4 and hMC5, respectively in CHO cells. [D-Trp8]-γ-MSH could provide protection...
BLT-1, a thiosemicarbazone copper chelator, is a selectivescavenger receptor B, type 1 (SR-BI)inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1...
L002 is a potent, cell permeable, reversible and specificacetyltransferase p300 (KAT3B)inhibitor with an IC50 of 1.98μM. L002 binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain, blocks his...
YN330043 NO-prednisolone 327610-87-7
NO-prednisolone is a nitric oxide (NO)-releasing derivative of Prednisolone. NO-prednisolone potently stimulatesIL-10production in vivo.
Col003 is a selective and potent inhibitor ofHsp47 and competitively binds to the collagen binding site on Hsp47 (IC50=1.8μM). Col003 discourages the interaction of Hsp47 with collagen and inhibits collagen secretion by desta...
C-178 is a covalent inhibitor of STING,covalently bind to Cys91.
YN372566 Lirimilast 329306-27-6
Lirimilast (BAY 19-8004) is a potent, selective and orally activephosphodiesterase-4 (PDE4)inhibitor with an IC50 value of 49nM. Lirimilast can be used for the treatment of asthma or chronic obstructive pulmonary disease (CO...
YN251586 7-O-Methylaloeresin A 329361-25-3
7-O-Methylaloeresin A is 5-methylchromone glycoside isolated fromCommiphora socotrana(Burseraceae). 7-O-Methylaloeresin A exhibits good activity against multiple drug resistantStaphylococcus aureus(NCTC 11994) and Salmonella...
TTP22 is a casein kinase 2 (CK2) inhibitor with an IC50 value of 100 nM. It displays selectivity for CK2 over JNK3, ROCK1, and MET with no inhibitory effects towards these kinases at 10 μM.
YN360647 PCI 29732 330786-25-9
PCI 29732 is a selective and irreversible Btk inhibitor with an IC50 of 0.5 nM.
TELL : +86-020-82000279
Add:Room 519, Block F, Guangzhou International Business Incubator, No.3 Lanyue Road, Science Town, Huangpu District, Guangzhou, China.
