YN480272 Rusalatide acetate 875455-82-6

Rusalatide acetate (TP508 amide acetate), a regenerative peptide, mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity.

YN370329 LXR-623 875787-07-8

LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier.

YN360528 Lesinurad 878672-00-5

Lesinurad is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout in combination with xanthine oxidase inhibitors.

YN483137 S-Dihydrodaidzein 879559-75-8

S-Dihydrodaidzein is the (S)-enantiomer of dihydrodaidzein which is one of the most prominent dietary phytoestrogens.

YN320696 Olmesartan medoxomil impurity... 879562-26-2

Olmesartan medoxomil impurity C is an Olmesartan medoxomil impurity. Olmesartan medoxomil is a potent and selectiveangiotensin AT1 receptorinhibitor with IC50 of 66.2μM.

YN480532 Lith-O-Asp 881179-02-8

Lith-O-Asp is asialytransferase (ST)inhibitor, with IC50s of 12-37μM.

YN350032 BI-78D3 883065-90-5

BI-78D3 is a competitive JNK inhibitor with IC50 of 280 nM that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K.

YN373313 N-​Benzyllinolenamide 883715-18-2

N-​Benzyllinolenamide is a natural macamide isolated fromLepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH) with an IC50 of 41.8μM.

YN373381 N-Benzyloleamide 883715-21-7

N-Benzyloleamide is a maccamide isolated fromLepidium meyenii(Maca). N-Benzyloleamide irreversibly inhibits fatty acid amide hydrolase(FAAH). N-benzyloleamide influences the energy metabolism and reveals antioxidant and antif...

YN450148 N-(3-Methoxybenzyl)-(9Z,12Z... 883715-23-9

N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide is a macamide isolated from Maca (Lepidium meyeniiWalp.) N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide induces mesenchymal stem cells osteogenic differentiation and c...

YN321010 GW9508 885101-89-3

GW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7.32, 100-fold selective against GPR120, stimulates insulin secretion in a glucose-sensitive manner.

YN483760 TB500 885340-08-9

TB500 is a synthetic version of an active region of thymosin β4. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation.

YN320214 Ridaifen-B 886465-70-9

Ridaifen-B (RID-B) is a potent antagonist ofestrogen receptor α (ERα)with IC50 of 52.4nM, a tamoxifen (HY-13757A) derivative. Ridaifen-B is a high affinity, selective, inverse agonist atCB2receptor (Ki=43.7nM) over 17...

YN481207 O-Methyl Atorvastatin hemic... 887196-29-4

O-Methyl Atorvastatin (hemicalcium) is an impurity of Atorvastatin. Atorvastatin is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, has the ability to effectively decrease blood lipids.

YN310082 OSS_128167 887686-02-4

OSS_128167 is a specific SIRT6 inhibitor with IC50 values of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, respectively.

YN330530 Epiberberine chloride 889665-86-5

Epiberberine chloride is an alkaloid isolated fromCoptis chinensis, acts as a potentAChE and BChEinhibitor, and a non-competitiveBACE1inhibitor, with IC50s of 1.07, 6.03 and 8.55μM, respectively. Epiberberine chloride h...

YN482850 Dipsanoside A 889678-62-0

Dipsanoside A is a novel tetrairidoid glucoside fromDipsacus asper.Dipsacus asperWall., a perennial plant widespread in China, has been used in traditional Chinese medicine for hundreds of years as a tonic for refreshment, as a fissi...

YN322084 CB1 antagonist 1 890037-68-0

CB1 antagonist 1 is an antagonist ofCB1 receptor, used in the research of metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, gastrointestinal disorders, and cardiovascular conditions.

YN370479 S3QEL-2 890888-12-7

S3QEL-2, a suppressor ofsuperoxide productionfrom mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7μM). S3QEL-2 does not affect oxidative phosphorylation, and no...

YN372643 AZD3988 892489-52-0

AZD3988 is adiacylglycerol acyl transferase-1 (DGAT-1)inhibitor with IC50s of 6, 5, 11nM for human, rat, mouse, respectively.